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Creating Radio-cephalic Arteriovenous Fistula in the Forearm with a Modified No-Touch Technique
Published on: April 1, 2022
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Arterial stiffness alone does not explain arteriovenous fistula outcomes
Damian G McGrogan1, Stephanie Stringer2, Paul Cockwell2
11 Department of Vascular Access and Renal Transplantation, University Hospitals Birmingham, Queen Elizabeth Hospital, Edgbaston, Birmingham - UK.
The Journal of Vascular Access
|October 28, 2017
Summary
Arterial stiffness markers, like higher augmentation index, predict successful arteriovenous fistula (AVF) patency. Stiffer vessels may be linked to AVF failure in end-stage renal disease patients.
Area of Science:
- Vascular Surgery
- Nephrology
- Cardiology
Background:
- Arterial adaptation is crucial for arteriovenous fistula (AVF) blood flow.
- Evaluating arterial disease markers can predict early AVF outcomes.
Purpose of the Study:
- To assess arterial disease markers and their association with early post-operative AVF outcomes.
Main Methods:
- Patients from the Renal Impairment In Secondary Care (RIISC) study with AVFs were included.
- Pulse wave analysis (BP Tru, Vicorder) and advanced glycation end-product assays were performed.
- Primary AVF failure (PFL) was defined as thrombosis at six-week review.
Main Results:
- Higher body mass index (BMI) and greater intraluminal vein diameter were observed in the primary patency (PPT) group.
- The PPT group showed significantly higher augmentation index values.
- Advanced glycation end-products did not significantly differ between groups; logistic regression predicted 78.1% of AVF patency.
Conclusions:
- End-stage renal disease patients exhibit significant aortic stiffness.
- Slower pulse wave velocity in the PPT group suggests a trend towards stiffer vessels correlating with PFL.
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