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Skin Cancer

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

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Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery

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Multiple primary melanoma: a single centre retrospective review.

Stephanie Menzies¹, Rupert Barry, Patrick Ormond

¹Department of Dermatology, St James' Hospital, Dublin, Republic of Ireland.

Melanoma Research

|October 28, 2017

Summary

Patients with multiple primary melanomas often have thinner, less advanced tumors. Regular skin surveillance is crucial, as 70% of second melanomas are diagnosed within two years of the first.

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Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography

Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography

Published on: December 2, 2022

Area of Science:

Dermatology
Oncology
Epidemiology

Background:

Multiple primary melanomas are associated with a poorer prognosis compared to single melanoma diagnoses.
Previous research suggests older white men are at increased risk for multiple primary melanomas.

Purpose of the Study:

To analyze the clinical characteristics and diagnostic patterns of patients with multiple primary melanomas.
To evaluate the time interval and characteristics of subsequent melanoma diagnoses.

Main Methods:

Retrospective analysis of 2057 melanoma cases diagnosed between January 1994 and March 2016.
Identification of 99 patients (4.8%) with multiple primary melanomas.
Comparison of tumor characteristics (Breslow thickness, Clark level, subtype, site) and patient demographics.

Main Results:

Subsequent melanomas were more frequently in situ and thinner (Breslow thickness, Clark level) than initial melanomas.
Superficial spreading and lentigo maligna were the most common subtypes; lower limbs were the most common site.
The average time between first and second melanoma diagnosis was 33.7 months, with 70% diagnosed within 2 years.

Conclusions:

Patients diagnosed with melanoma require ongoing skin surveillance due to the high likelihood of developing a second primary melanoma within two years.
Subsequent melanomas may present with less aggressive features, underscoring the need for vigilant monitoring regardless of initial tumor characteristics.