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Exploration on the relationship between the elderly osteoporosis and cardiovascular disease risk factors

X-L Lian1, Y-P Zhang, X Li

  • 1Department of Cardiology, People's Hospital of Qinghai Province, Qinghai, China. 2648075086@qq.com.

European Review for Medical and Pharmacological Sciences
|October 28, 2017
PubMed

Insights

Elderly osteoporosis is linked to cardiovascular disease risk factors like hypertension and hyperlipidemia. Early prevention and treatment are crucial for managing these interconnected conditions in older adults.

Area of Science:

  • Gerontology
  • Cardiology
  • Endocrinology

Background:

  • Osteoporosis and cardiovascular diseases (CVD) are prevalent in the elderly.
  • Shared risk factors may link these two conditions.
  • Understanding this correlation is vital for geriatric health.

Purpose of the Study:

  • To investigate the association between osteoporosis and cardiovascular disease risk factors in elderly individuals.
  • To identify specific risk and protective factors for osteoporosis in this demographic.

Main Methods:

  • A cohort of 1240 elderly patients (≥65 years) was analyzed.
  • Patients were categorized into osteoporosis and normal bone mass groups based on bone mineral density.
  • General conditions, biochemical markers, CVDs, and risk factors were recorded and statistically analyzed.

Main Results:

  • The osteoporosis group showed significantly higher rates of coronary heart disease, hyperlipidemia, diabetes mellitus, and smoking compared to the normal bone mass group (p < 0.05).
  • Homocysteine (HCY), low-density lipoprotein (LDL), and total cholesterol (TC) were identified as major osteoporosis risk factors.
  • High-density lipoprotein (HDL) and body weight acted as protective factors. Female sex, hypertension, coronary heart disease, hyperlipidemia, and diabetes mellitus were key risk factors for complications in osteoporotic elderly patients.

Conclusions:

  • Senile osteoporosis is strongly correlated with cardiovascular diseases and their associated risk factors, including hypertension, coronary heart disease, and hyperlipidemia.
  • Early detection, prevention, and treatment strategies are recommended for managing osteoporosis and mitigating cardiovascular risks in the elderly.
Abstract

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