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Updated: Feb 20, 2026

Postconditioning with Lactate-enriched Blood for Cardioprotection in ST-segment Elevation Myocardial Infarction
Published on: May 28, 2019
[Non-ST-Segment Elevation Myocardial Infarction Caused by Spontaneous Coronary Thrombosis by Intimal Rupture]
Insights
Spontaneous coronary artery dissection (SCAD) caused a patient's coronary thrombosis, presenting as acute thoracic pain. SCAD is a crucial consideration for acute coronary syndrome (ACS) diagnosis.
Area of Science:
- Cardiology
- Vascular Medicine
Background:
- Acute coronary syndrome (ACS) necessitates timely diagnosis and treatment.
- Spontaneous coronary artery dissection (SCAD) is an underrecognized cause of ACS, particularly in younger individuals or those without traditional cardiovascular risk factors.
Observation:
- A 51-year-old male presented with acute thoracic pain radiating to the left arm, accompanied by elevated troponin levels.
- Cardiac catheterization revealed a medial filling defect in the RIVA, and OCT imaging demonstrated intimal rupture with thrombus formation.
Findings:
- The patient's coronary thrombosis was diagnosed as SCAD.
- Successful stenting with a drug-eluting stent and medical management (aspirin, ticagrelor, metoprolol, simvastatin) were initiated.
Implications:
- SCAD should be considered in the differential diagnosis of ACS, even in patients with cardiovascular risk factors.
- Further research and updated clinical guidelines are essential for optimizing SCAD management.
Abstract:
Medical history We report on a 51-year-old male patient with thoracic pain of acute onset with radiation in the left arm. His cardiovascular risk factors include obesity, smoking and arterial hypertension. Investigations ECG showed no signs of ischemia. The blood test revealed increasing troponin (37 pg/ml; Norm < 14 pg/ml). Therefore we performed cardiac catheterization. The RIVA demonstrated a medial filling defect. Use of OCT imaging showed intimal rupture associated with thrombus. Treatment and course The lesion was stented with a drug eluting stent. We initiated a medication with aspirin, ticagrelor, metoprolol and simvastatin. Conclusion Coronary thrombosis of our patient was caused by spontaneous coronary artery dissection (SCAD). SCAD is an important differential diagnosis in patients with ACS. Further prospective studies and guideline recommendations are needed in the future.
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