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Related Concept Videos

Drugs for Treatment of Constipation-Predominant IBS01:21

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Pharmacological therapies for IBS-C are designed to alleviate abdominal discomfort and enhance bowel function. In patients with IBS-C, fiber supplements may help soften stools and decrease straining, but may also lead to increased gas production and bloating. Osmotic laxatives like milk of magnesia are frequently used to soften stools and increase stool frequency in IBS-C patients. In addition, two drugs approved for use in severe IBS-C adult cases are linaclotide (Linzess) and lubiprostone...
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Electroacupuncture Combined with Chinese Medicine Ironing Therapy for Functional Constipation
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Idiopathic constipation: A challenging but manageable problem.

Andrea Bischoff1, Giulia Brisighelli2, Belinda Dickie3

  • 1International Center for Colorectal and Urogenital Care, Children's Hospital Colorado, Aurora, CO, USA.

Journal of Pediatric Surgery
|October 29, 2017
PubMed
Summary
This summary is machine-generated.

This study presents a successful protocol for treating idiopathic constipation in children. The method involves a clean-out phase, individualized Senna laxative dosing, and radiological monitoring for effective colon emptying.

Keywords:
Bowel managementEncopresisIdiopathic constipationLaxativeSenna

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Area of Science:

  • Pediatric Gastroenterology
  • Clinical Protocol Development

Background:

  • Idiopathic constipation is a common condition in children, often leading to encopresis.
  • Effective management requires a tailored approach to laxative therapy.

Purpose of the Study:

  • To present a novel protocol for the management of idiopathic constipation in pediatric patients.
  • To evaluate the efficacy and success rates of the proposed treatment protocol.

Main Methods:

  • A contrast enema was performed, followed by a "clean out" protocol when indicated.
  • Patients received Senna-based laxatives with empirically determined, daily adjusted dosages over one week.
  • Success was defined by daily colon emptying and cessation of soiling, with radiological monitoring of colonic emptying.

Main Results:

  • Out of 215 treated patients, 84% achieved successful management within one week.
  • The average Senna dose for successful management was 67mg.
  • At a later follow-up, the overall success rate remained high at 81%.

Conclusions:

  • The developed protocol for idiopathic constipation is effective and successful.
  • Key elements for success include initial "clean out," individualized laxative titration, and radiological assessment.