Related Experiment Video
Updated: Feb 19, 2026
06:11
Therapy Testing in a Spheroid-based 3D Cell Culture Model for Head and Neck Squamous Cell Carcinoma
Published on: April 20, 2018
10.3K
The Case Volume Issue in Head and Neck Oncology
Salvatore Alfieri1, Ester Orlandi2, Paolo Bossi3
1Head and Neck Medical Oncology Department, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy.
Current Treatment Options in Oncology
|October 29, 2017
Summary
Managing head and neck cancer (HNC) patients at high-volume cancer referral centers (CRCs) improves outcomes. Case volume, influenced by hospital expertise and professional skill, is key to better HNC treatment results.
Area of Science:
- Oncology
- Health Services Research
Background:
- Evidence suggests improved outcomes for head and neck cancer (HNC) patients treated at high-volume cancer referral centers (CRCs).
- Benefits include reduced toxicities and longer survival, observed in patients undergoing surgery, radiotherapy, or chemotherapy.
Purpose of the Study:
- To explore the impact of case volume on HNC patient outcomes.
- To discuss factors contributing to improved results at high-volume centers and potential limitations of regionalization.
Main Methods:
- Review of existing evidence on the relationship between case volume and HNC patient outcomes.
- Discussion of organizational, professional, and technological factors influencing treatment efficacy.
Main Results:
- High-volume centers are associated with better HNC treatment outcomes, including reduced toxicity and enhanced survival.
- The definition and criteria for 'high-volume' remain debated, with potential biases in patient referral.
Conclusions:
- Case volume is a significant factor influencing the quality of head and neck cancer care.
- It should be considered a stratifying factor in future clinical trials for HNC patients.
Related Concept Videos
01:19Veins of Head and Neck
6.0K
The blood drainage from the head and neck is primarily managed by three pairs of veins: the external jugular, internal jugular, and vertebral veins. The external jugular veins drain superficial scalp and face structures, passing over the sternocleidomastoid muscles to empty into the subclavian veins.
On the other hand, the vertebral veins, unlike their arterial counterparts, are not primarily responsible for brain drainage. Instead, they drain the cervical vertebrae, spinal cord, and some small...
On the other hand, the vertebral veins, unlike their arterial counterparts, are not primarily responsible for brain drainage. Instead, they drain the cervical vertebrae, spinal cord, and some small...
6.0K
01:26Arteries of the Head and Neck
3.7K
The human body's intricate network of arteries ensures that every organ system receives the necessary oxygen and nutrients for optimal function. The arterial network in the head and neck region is particularly complex, providing vital blood flow to the brain, eyes, and other critical structures. Prominent arteries in this region include the internal carotid arteries and the vertebral arteries.
The internal carotid arteries supply blood to the anterior portion of the cerebrum. They enter the...
The internal carotid arteries supply blood to the anterior portion of the cerebrum. They enter the...
3.7K