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Osteopenia and the physical function in Japanese patients with schizophrenia
Satoru Uchida1, Tsuyoshi Ichinose2, Yoichi Iizuka3
1Department of Orthopaedic Surgery, Saint-Pierre hospital, Takasaki, Gunma, Japan.
Archives of Osteoporosis
|October 29, 2017
Summary
Osteopenia and physical function are worse in schizophrenic inpatients compared to outpatients. Elderly females with schizophrenia and low body mass index (BMI) are at higher risk for osteopenia.
Area of Science:
- Orthopedics
- Psychiatry
- Bone Metabolism
Background:
- Osteopenia prevalence and related factors in schizophrenia patients remain under-researched.
- Schizophrenia patients may experience poorer physical health, including bone health.
Purpose of the Study:
- To investigate osteopenia and physical function in schizophrenia patients.
- To compare osteopenia and physical function between inpatient and outpatient groups.
- To identify factors associated with osteopenia in this population.
Main Methods:
- 121 schizophrenia patients were assessed.
- Data collected included demographics, body mass index (BMI), bone mineral density (BMD), bone metabolic markers, fracture risk, and physical function.
- Patients were categorized into inpatient and outpatient groups.
Main Results:
- Inpatients exhibited higher fracture risk, lower BMI, and lower BMD (lumbar spine and proximal femur) than outpatients.
- Age, sex, BMI, vertebral fractures, and physical function scores correlated with BMD.
- Therapeutic form and bone metabolic markers did not correlate with BMD.
Conclusions:
- Schizophrenia inpatients show poorer bone health and physical function.
- Physicians should assess osteopenia risk in elderly female schizophrenia patients with low BMI.
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