Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Combined opiate/adrenergic receptor blockade enhances squirrel monkey vocalization.

J C Harris1, J D Newman

  • 1Division of Child Psychiatry, Johns Hopkins University, Baltimore, MD 21205.

Pharmacology, Biochemistry, and Behavior
|September 1, 1988
PubMed
Summary

Opiate and noradrenergic systems interact to influence primate vocalizations. Combined antagonists (yohimbine and naloxone) increased squirrel monkey twitters, but not isolation calls, suggesting complex neurochemical regulation.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Responsible research in health disparities using the Adolescent Brain Cognitive Development<sup>SM</sup> (ABCD) study.

Developmental cognitive neuroscience·2024
Same author

Clinical and technical factors in endoscopic skull base surgery associated with reconstructive success.

Rhinology·2024
Same author

Preliminary observations on squirrel monkey (Saimiri oerstedi) vocalizations in Costa Rica.

American journal of primatology·2020
Same author

Context and gender-specific differences in the acoustic structure of common marmoset (Callithrix jacchus) phee calls.

American journal of primatology·2020
Same author

Responses to natural and synthetic phee calls by common marmosets (Callithrix jacchus).

American journal of primatology·2020
Same author

Development of a binary vector system for plant transformation based on the supervirulent Agrobacterium tumefaciens strain Chry5.

Plant cell reports·2019

Area of Science:

  • Neuroscience
  • Primatology
  • Behavioral Biology

Background:

  • Opiate and noradrenergic systems are implicated in various behaviors.
  • Primate vocalizations offer a model for studying neurochemical influences on communication.

Purpose of the Study:

  • To investigate the interaction between opiate and noradrenergic systems on primate vocal behavior.
  • To determine the effects of combined alpha 2 adrenergic and opiate antagonists on specific vocalizations.

Main Methods:

  • Administration of yohimbine (alpha 2 adrenergic antagonist) and naloxone (opiate antagonist) to adult squirrel monkeys.
  • Quantification of vocalizations, specifically 'twitters' and 'isolation calls'.
  • Observation of autonomic symptoms.

Related Experiment Videos

Main Results:

  • Combined administration of yohimbine and naloxone synergistically increased the rate of 'twitters'.
  • No significant effect was observed on the 'isolation call'.
  • The drug combination induced an increase in autonomic symptoms.

Conclusions:

  • Evidence suggests an interaction between opiate and noradrenergic pathways in modulating primate 'twitter' vocalizations.
  • The specific anatomical localization and mechanistic basis for this interaction require further research.
  • The findings highlight the complex neurochemical underpinnings of primate communication.