Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Niemann-Pick disease with two missense mutations in SMPD1 gene: a case report and literature review].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi·2026
Same author

[Analysis of 8 children with TCF3:: HLF fusion gene positive acute lymphoblastic leukemia].

Zhonghua er ke za zhi = Chinese journal of pediatrics·2025
Same author

[Impact of pre-pregnancy BMI on the cumulative live birth rate and perinatal outcomes in patients with PCOS undergoing first IVF/ICSI].

Zhonghua fu chan ke za zhi·2025
Same author

[Application value of domestic single-port robot in nephron sparing surgery].

Zhonghua yi xue za zhi·2024
Same author

[Efficacy of venetoclax-based induction regimen in newly diagnosed pediatric acute myeloid leukemia].

Zhonghua yi xue za zhi·2024
Same author

Independent and combined effects of smoking, drinking and depression on periodontal disease.

BMC oral health·2024

Related Experiment Video

Updated: Feb 19, 2026

Assessment of Oxidative Damage in the Primary Mouse Ocular Surface Cells/Stem Cells in Response to Ultraviolet-C UV-C Damage
12:59

Assessment of Oxidative Damage in the Primary Mouse Ocular Surface Cells/Stem Cells in Response to Ultraviolet-C UV-C Damage

Published on: February 15, 2020

6.8K

[Oxidative damage effects induced by CdTe quantum dots in mice].

G Y Xie1, W Chen, Q K Wang

  • 1National Insititue of Occupational Health and Poison Control, Chinese Center for Disease Control and Prevention, Beijing 100050, China.

Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi = Zhonghua Laodong Weisheng Zhiyebing Zazhi = Chinese Journal of Industrial Hygiene and Occupational Diseases
|October 31, 2017
PubMed
Summary

Cadmium telluride quantum dots (CdTe QDs) exposure in mice at 0.5 nmol/ml concentration induced oxidative damage. Further research is needed to understand the full impact of CdTe QDs on biological systems.

Keywords:
CdTeMiceQuantum dots (QDs)Superoxide dismutose

More Related Videos

Solubilization and Bio-conjugation of Quantum Dots and Bacterial Toxicity Assays by Growth Curve and Plate Count
13:06

Solubilization and Bio-conjugation of Quantum Dots and Bacterial Toxicity Assays by Growth Curve and Plate Count

Published on: July 11, 2012

14.8K
Quantification of three DNA Lesions by Mass Spectrometry and Assessment of Their Levels in Tissues of Mice Exposed to Ambient Fine Particulate Matter
12:15

Quantification of three DNA Lesions by Mass Spectrometry and Assessment of Their Levels in Tissues of Mice Exposed to Ambient Fine Particulate Matter

Published on: May 29, 2019

9.2K

Related Experiment Videos

Last Updated: Feb 19, 2026

Assessment of Oxidative Damage in the Primary Mouse Ocular Surface Cells/Stem Cells in Response to Ultraviolet-C UV-C Damage
12:59

Assessment of Oxidative Damage in the Primary Mouse Ocular Surface Cells/Stem Cells in Response to Ultraviolet-C UV-C Damage

Published on: February 15, 2020

6.8K
Solubilization and Bio-conjugation of Quantum Dots and Bacterial Toxicity Assays by Growth Curve and Plate Count
13:06

Solubilization and Bio-conjugation of Quantum Dots and Bacterial Toxicity Assays by Growth Curve and Plate Count

Published on: July 11, 2012

14.8K
Quantification of three DNA Lesions by Mass Spectrometry and Assessment of Their Levels in Tissues of Mice Exposed to Ambient Fine Particulate Matter
12:15

Quantification of three DNA Lesions by Mass Spectrometry and Assessment of Their Levels in Tissues of Mice Exposed to Ambient Fine Particulate Matter

Published on: May 29, 2019

9.2K

Area of Science:

  • Nanomaterials Science
  • Toxicology
  • Biochemistry

Background:

  • Cadmium telluride quantum dots (CdTe QDs) are increasingly used in biomedical applications.
  • Understanding their potential toxicity, particularly oxidative damage, is crucial.

Purpose of the Study:

  • To investigate the oxidative damage effects induced by CdTe QDs in mice.
  • To determine the dose-dependent toxicity of CdTe QDs.

Main Methods:

  • Forty ICR mice were divided into five groups, including a control and four groups exposed to varying concentrations of CdTe QDs (0.5, 5.0, 50.0, 500.0 nmol/ml) via intravenous injection.
  • Blood samples were collected 24 hours post-exposure for biochemical and hematological analysis, including superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) activity, and malondialdehyde (MDA) concentration.

Main Results:

  • CdTe QDs exposure at 0.5 nmol/ml significantly altered biochemical and hematological indexes.
  • Increased MDA concentration and altered SOD and GSH-Px activities were observed, indicating oxidative stress.
  • Specific changes included significantly lower levels of CRE and PLT, and significantly higher GSH-Px activity at higher CdTe QD concentrations.

Conclusions:

  • CdTe QDs, even at a low concentration of 0.5 nmol/ml, can induce oxidative damage in mice.
  • The findings highlight the need for careful risk assessment of CdTe QDs in biological applications.