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Updated: Feb 19, 2026

Deep Learning-Based Segmentation of Cryo-Electron Tomograms
Published on: November 11, 2022
Automatic Segmentation of Ultrasound Tomography Image
Shibin Wu1,2, Shaode Yu1,2, Ling Zhuang3
1Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, 1068 Xueyuan Avenue, Shenzhen University Town, Shenzhen 518055, China.
Abstract:
Ultrasound tomography (UST) image segmentation is fundamental in breast density estimation, medicine response analysis, and anatomical change quantification. Existing methods are time consuming and require massive manual interaction. To address these issues, an automatic algorithm based on GrabCut (AUGC) is proposed in this paper. The presented method designs automated GrabCut initialization for incomplete labeling and is sped up with multicore parallel programming. To verify performance, AUGC is applied to segment thirty-two in vivo UST volumetric images. The performance of AUGC is validated with breast overlapping metrics (Dice coefficient (D), Jaccard (J), and False positive (FP)) and time cost (TC). Furthermore, AUGC is compared to other methods, including Confidence Connected Region Growing (CCRG), watershed, and Active Contour based Curve Delineation (ACCD). Experimental results indicate that AUGC achieves the highest accuracy (D = 0.9275 and J = 0.8660 and FP = 0.0077) and takes on average about 4 seconds to process a volumetric image. It was said that AUGC benefits large-scale studies by using UST images for breast cancer screening and pathological quantification.

