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Acute pancreatitis after coronary artery bypass surgery treated by plasmapheresis

Emine Şeyma Denli Yalvaç1, Mustafa Aldağ1, Cemal Kocaaslan1

  • 1Department of Cardiovascular Surgery, İstanbul Medeniyet University Göztepe Training and Research Hospital, İstanbul, Turkey.

The Turkish Journal of Gastroenterology : the Official Journal of Turkish Society of Gastroenterology
|October 31, 2017
PubMed

Insights

Acute pancreatitis (AP) after coronary artery bypass grafting (CABG) is rare but serious. Plasmapheresis, a blood cleansing technique, successfully treated a severe AP case without hypertriglyceridemia.

Area of Science:

  • Cardiology
  • Gastroenterology
  • Critical Care Medicine

Background:

  • Acute pancreatitis (AP) is a significant cause of morbidity and mortality.
  • AP following coronary artery bypass grafting (CABG) is infrequent but carries a high mortality risk due to atypical presentations.
  • Standard treatments for AP include supportive care, pain management, and complication management.

Observation:

  • A 60-year-old male developed severe AP (Ranson Score: 6) post-CABG without hypertriglyceridemia.
  • Conventional supportive therapy yielded an unpredictable response.
  • Plasmapheresis was initiated as an alternative treatment modality.

Findings:

  • The patient showed a successful response to plasmapheresis treatment.
  • This represents a novel application of plasmapheresis for AP unrelated to hypertriglyceridemia.
  • The treatment was both efficient and safe in this clinical scenario.

Implications:

  • Plasmapheresis may be a viable and effective treatment option for select cases of AP, particularly those with severe presentations and no response to conventional therapy.
  • This case expands the known therapeutic applications of plasmapheresis in critical care settings.
  • Further research into plasmapheresis for non-hypertriglyceridemic AP is warranted.

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