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Ugi Multicomponent Reaction Based Synthesis of Medium-Sized Rings

Eman M M Abdelraheem1,2, Rudrakshula Madhavachary1, Arianna Rossetti1

  • 1Department of Drug Design, University of Groningen , A. Deusinglaan 1, 9713 AV Groningen, The Netherlands.

Organic Letters
|October 31, 2017
PubMed
Summary

A novel two-step strategy efficiently creates medium-sized rings using the Ugi multicomponent reaction. This approach synthesizes complex cyclic structures from readily available starting materials under mild conditions.

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