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No increase in free fetal DNA level in ectopic pregnancy: A preliminary study
Özge Kömürcü Karuserci1, Mete Gürol Uğur1, Özcan Balat1
1Gaziantep University Faculty of Medicine, Department of Obstetric and Gynecology, Gaziantep, Turkey.
Objective:
The aim of this study was to diagnose ectopic pregnancy in the early period by measuring cell-free fetal DNA (cffDNA) levels in maternal blood using spectrophotometry.
Materials And Methods:
Thirty patients with ectopic pregnancy and 30 patients with first trimester intrauterine pregnancy were enrolled in this prospective controlled study. cffDNA levels in maternal serum were measured using spectrophotometry.
Results:
There were no differences between the two groups in terms of cffDNA absorbance levels.
Conclusion:
Spectrophotometry is not suitable for measuring cffDNA levels to diagnose ectopic pregnancies in the early period. Practical and cost-effective methods should be found or larger patient series should be investigated.
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