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A Computational Library Design Protocol for Rapid Improvement of Protein Stability: FRESCO

Hein J Wijma1, Maximilian J L J Fürst2, Dick B Janssen3

  • 1Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Nijenborgh 4, 9747, Groningen, The Netherlands. h.j.wijma@rug.nl.

Methods in Molecular Biology (Clifton, N.J.)
|November 1, 2017
PubMed

Keywords:
BiocatalysisBiotransformationComputational designDirected evolutionIn silico screeningMutant design strategyProtein engineeringSmart libraryStabilizationThermostability

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