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Updated: Feb 19, 2026

Rapid Detection of Neurodevelopmental Phenotypes in Human Neural Precursor Cells NPCs
Published on: March 2, 2018
[NEURODEVELOPMENT DISORDERS AND POSSIBILITY OF THEIR PRENATAL DETECTION]
Abstract:
Neurodevelopment disorders including cerebral palsy are a group of non-progressive and noninfectious diseases characterized by different levels of abnormal neurodevelopment. Most often, diagnosis is made at the age of 5 years or later. It has been recognized that most of the cerebral damages appear prenatally. This fact stimulated researchers all over the world to detect the possible causes in utero. These studies have been possible due to the development of ultrasound technology in real time and display of fetal mobility. Thanks to the development of four-dimensional (4D) ultrasound, prenatal screening neurological test was developed. The test is based on assessment of the number and quality of spontaneous movements of the fetus. The question arises whether fetal behavior, observed on 4D ultrasound, reflects neurological development of the fetus in a manner that will allow detection of brain damage in utero.
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