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Tumor Necrosis Factor-α Induces Monocyte Chemoattractant Protein-1 mRNA in a Schwann Cell Line

M C Subang1, P M Richardson1

  • 1Montreal General Hospital Research Institute and McGill University, 1650 Cedar Avenue, Montreal, Quebec, Canada H3G 1A4.

Annals of the New York Academy of Sciences
|November 1, 2017
PubMed
Abstract

No abstract available in PubMed .

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Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
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