Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Accessory Structures of the Skin: Hair Growth and Types01:20

Accessory Structures of the Skin: Hair Growth and Types

2.6K
Hair growth begins with the production of keratinocytes by the basal cells of the hair bulb. As new cells are deposited at the hair bulb, the hair shaft is pushed through the follicle toward the surface. Keratinization is completed as the cells are pushed to the skin surface to form the shaft of hair that is externally visible. The external hair is completely dead and composed entirely of keratin. Hair can be cut or shaven without damaging the hair structure because the cut is superficial. Most...
2.6K
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

5.8K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
5.8K
Multipotency and Niche of Bulge Stem Cell01:06

Multipotency and Niche of Bulge Stem Cell

4.3K
A hair follicle or HF is a small part of the skin that produces the hair shaft. Paul Gerson Unna was the first to observe a bulge in the human hair follicle's outer root sheath (ORS). The bulge is present between the sebaceous gland and the arrector pili muscle and is the niche for hair follicle stem cells (HFSCs). The bulge is also a niche for melanocyte stem cells, and their loss results in graying of hair. The HFSCs express Sox9 and Lhx2, which help them maintain stemness and prevent...
4.3K
Tissue Transplantation01:24

Tissue Transplantation

1.1K
Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
1.1K
Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

3.9K
The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
3.9K
Autoimmune Disorders01:29

Autoimmune Disorders

1.9K
Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune...
1.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Antibiotic risk assessment in agricultural soil from Tamaulipas, Mexico.

Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes·2026
Same author

Specific gene expression patterns associated as reliable biomarkers for predicting dental implant successful osseointegration: a literature review and focused meta-analysis.

Frontiers in physiology·2026
Same author

Occurrence of Virulence and Antibiotic Resistance in <i>Pseudomonas aeruginosa</i> Isolated from the Environmental Water from Tamaulipas, Mexico.

Antibiotics (Basel, Switzerland)·2025
Same author

Distribution of phylogroups and antibiotic resistance patterns of ESBL-producing Escherichia coli strains isolated from chicken meat in Tamaulipas, Mexico.

Acta microbiologica et immunologica Hungarica·2025
Same author

Antimicrobial resistance and virulence factors of Listeria monocytogenes isolated from fresh cheese products in Tamaulipas, Mexico.

Acta microbiologica et immunologica Hungarica·2025
Same author

Insights from a Genome-Wide Study of <i>Pantoea agglomerans</i> UADEC20: A Promising Strain for Phosphate Solubilization and Exopolysaccharides Production.

Current issues in molecular biology·2025

Related Experiment Video

Updated: Feb 19, 2026

A New Technique for Quantitative Analysis of Hair Loss in Mice Using Grayscale Analysis
06:41

A New Technique for Quantitative Analysis of Hair Loss in Mice Using Grayscale Analysis

Published on: March 9, 2015

9.5K

Alopecia Areata. Current situation and perspectives.

Karina J Juárez-Rendón1,2, Gildardo Rivera Sánchez2, Miguel Á Reyes-López2

  • 1Consejo Nacional de Ciencia y Tecnología (CONACYT). kjgenetic2012@gmail.com.

Archivos Argentinos De Pediatria
|November 1, 2017
PubMed
Summary

Alopecia areata is an unpredictable hair loss condition. This review explores its clinical features, causes, and genetic links, offering an updated overview for patients and researchers.

Keywords:
Alopecia Areatagenessusceptibility

More Related Videos

Mechanical and Controlled PRP Injections in Patients Affected by Androgenetic Alopecia
03:22

Mechanical and Controlled PRP Injections in Patients Affected by Androgenetic Alopecia

Published on: January 27, 2018

15.7K
Isolation and Culture of Adult Epithelial Stem Cells from Human Skin
08:26

Isolation and Culture of Adult Epithelial Stem Cells from Human Skin

Published on: March 31, 2011

29.0K

Related Experiment Videos

Last Updated: Feb 19, 2026

A New Technique for Quantitative Analysis of Hair Loss in Mice Using Grayscale Analysis
06:41

A New Technique for Quantitative Analysis of Hair Loss in Mice Using Grayscale Analysis

Published on: March 9, 2015

9.5K
Mechanical and Controlled PRP Injections in Patients Affected by Androgenetic Alopecia
03:22

Mechanical and Controlled PRP Injections in Patients Affected by Androgenetic Alopecia

Published on: January 27, 2018

15.7K
Isolation and Culture of Adult Epithelial Stem Cells from Human Skin
08:26

Isolation and Culture of Adult Epithelial Stem Cells from Human Skin

Published on: March 31, 2011

29.0K

Area of Science:

  • Dermatology
  • Immunology
  • Genetics

Background:

  • Alopecia areata (AA) is a non-scarring hair loss condition affecting the scalp and body.
  • The exact cause of AA remains unknown, but environmental, immunological, and genetic factors are suspected.
  • The disease course is unpredictable and variable among patients.

Purpose of the Study:

  • To provide an updated overview of alopecia areata's clinical characteristics.
  • To review diagnostic and treatment strategies for AA.
  • To analyze potential etiological mechanisms and genetic susceptibility factors for AA.

Main Methods:

  • Literature review of clinical studies and genetic research on alopecia areata.
  • Analysis of current understanding of AA pathogenesis.
  • Synthesis of information on genetic variants associated with AA susceptibility.

Main Results:

  • The review synthesizes current knowledge on AA's clinical presentation, diagnosis, and treatment options.
  • It examines the immunological and environmental factors implicated in AA.
  • Key genetic variants contributing to AA susceptibility are highlighted.

Conclusions:

  • Alopecia areata is a complex condition with multifactorial origins.
  • Further research into genetic and environmental factors is crucial for understanding AA.
  • An updated understanding aids in managing and potentially treating alopecia areata.