Related Experiment Video
Updated: Feb 19, 2026
Creation of Abdominal Adhesions in Mice
Published on: August 27, 2016
[Labial adhesions: review of the literature]
Samuel D Barbosa Ardila1, Alexander I Tristancho Baró2, José M Suescún Vargas3
1Grupo de Investigación en Ciencias Pediátricas Aplicadas del Instituto Roosevelt.
Insights
Labial adhesion (sinequia vulvae) is a common, benign pediatric condition. Treatment options range from observation to topical therapies and surgical separation, with surgery offering the highest success rate and lowest recurrence.
Area of Science:
- Pediatric Gynecology
- Dermatology
Background:
- Labial adhesion, or sinequia vulvae, is a frequent benign finding in pediatric females.
- Incidence ranges from 0.3% to 3.3%, predominantly affecting children aged 3 months to 6 years.
Purpose of the Study:
- To conduct an extensive review of international literature.
- To analyze risk factors, etiology, treatment modalities, and prognosis of labial adhesions.
Main Methods:
- Systematic literature search performed in PubMed, Embase, and Science Direct.
- Included studies published between January 1999 and October 2016.
Main Results:
- Labial adhesion is a multicausal benign pathology with limited research from Latin America.
- Topical treatments show variable success rates: conjugated estrogens (50-90% success, 30% recurrence) and corticoids (68-80% success, 23% recurrence).
Conclusions:
- Surgical separation achieves a 100% success rate with a 10% recurrence rate.
- Management strategies include observation, topical treatments, and surgical intervention.
Introduction:
Fusion of the labia or sinequia vulvae is a common and benign finding in the pediatric female population. The reported incidence is 0.3-3.3% with a greater incidence between 3 months and 6 years old.
Objetive:
Extensive review of the current international literature regarding the risk factors, etiology, treatment and prognosis.
Materials And Methods:
A systematic search in medical databases as PubMed, Embase and Science Direct for the papers published between January 1999 and October 2016.
Results And Conclusions:
Labial adhesion is a multicausal benign pathology and there were very few published studies in Latin America. The proposed lines of treatment are observation and periodic follow up, topical treatment and manual or surgical separation. Topical conjugated estrogens have a success rate of 50-90% with recurrence of 30% and topical corticoids reported 68-80% of success with 23% of recurrences. Surgical intervention has a success rate of 100% and recurrence of 10%.
Related Concept Videos
01:14Adhesion
Capillary action is a result of water’s adhesive tendencies. When a narrow...
01:24Adherens Junctions
Adherens Junctions are Dynamic