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Influenza A Infection and Anaphylaxis in a Pediatric Patient Hospitalized for Asthma Exacerbation
1Departments of Medicine and Pediatrics, Warren Alpert Medical School of Brown University; Rhode Island Hospital and Hasbro Children's Hospital, Providence, RI.
Insights
This case study highlights a rare instance of anaphylaxis in a child with influenza A infection. Early recognition and treatment of influenza may prevent severe allergic reactions.
Area of Science:
- Pediatrics
- Infectious Diseases
- Allergy and Immunology
Background:
- Influenza infections can lead to systemic complications beyond respiratory issues.
- Anaphylaxis is a severe allergic reaction, rarely linked to viral infections.
- Previous reports of viral-induced anaphylaxis are scarce, with none documented for influenza.
Abstract:
Influenza infections can cause a variety of different systemic problems beyond respiratory symptoms. A 4-year-old boy with a history of atopy, infected with influenza A, presented to our hospital with an asthma exacerbation developed symptoms of anaphylaxis. He was treated with a full course of oseltamivir and symptoms resolved without recurrence of allergic reaction. Infections have been implicated as causes of anaphylaxis but this has mostly been limited to parasites. While viral infections have been documented as causes of urticarial rashes, anaphylaxis due to viral infection has only been reported once, in an adult patient. There have not been any reports of anaphylaxis related to influenza infections. Early recognition and treatment of patients with influenza may prevent progression of systemic allergic reactions. [Full article available at http://rimed.org/rimedicaljournal-2017-11.asp].
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