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Experimental chemotherapy and radiotherapy to paratesticular rhabdomyosarcoma
T Motoyama1, H Watanabe, T Watanabe
1Department of Pathology, Niigata University School of Medicine, Japan.
The Journal of Urology
|January 1, 1989
Abstract:
Experimental chemotherapy and radiotherapy were tried in transplanted tumors derived from a paratesticular embryonal rhabdomyosarcoma. There was no significant difference on the therapeutic effect between a combination chemotherapy composed of vincristine, actinomycin D and cyclophosphamide, so-called "VAC" regimen, and a single therapy of radiation. However, morphologic analyses suggest that VAC is effective in embryonal rhabdomyosarcomas in which undifferentiated rhabdomyoblasts predominate, while radiotherapy is preferable for those containing variously differentiated rhabdomyoblasts.