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Cell Population Analyses During Skin Carcinogenesis
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Nonsyndromic Multiple Basal Cell Carcinomas.

Dong Hwi Kim1, Hyo Sun Ko1, Young Joon Jun1

  • 1Department of Plastic and Reconstructive Surgery, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.

Archives of Craniofacial Surgery
|November 2, 2017
PubMed
Summary
This summary is machine-generated.

Multiple basal cell carcinoma (BCC) with parotid invasion is rare. This report details two cases, including a unique instance of parotid invasion linked solely to actinic keratosis, highlighting the importance of early BCC diagnosis and treatment.

Keywords:
Basal cell carcinoma, multipleBasal cell carcinoma, nonsyndromicSkin neoplasms

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Area of Science:

  • Dermatology
  • Oncology

Background:

  • Multiple basal cell carcinoma (BCC) lesions are common, but nonsyndromic BCC with parotid gland invasion is exceptionally rare.
  • Actinic keratosis can also present as multiple lesions and may precede or coexist with BCC.

Purpose of the Study:

  • To report two rare cases of multiple, sporadic, nonsyndromic basal cell carcinoma.
  • To highlight a unique case of parotid invasion associated with actinic keratosis.

Main Methods:

  • Surgical excision of multiple skin lesions.
  • Pathological examination of excised tissue for diagnosis of basal cell carcinoma and actinic keratosis.

Main Results:

  • Case 1: A 79-year-old female with multiple BCC and actinic keratosis, later developing squamous cell carcinoma in situ and actinic keratosis in new lesions.
  • Case 2: A 43-year-old female with multiple BCC lesions diagnosed via surgical excision and pathology.
  • One presented with parotid invasion linked to actinic keratosis.

Conclusions:

  • Multiple basal cell carcinoma, especially with parotid invasion, represents a rare clinical scenario.
  • Early diagnosis and treatment of basal cell carcinoma are crucial to prevent disfigurement and destruction, even in non-metastatic cases.