Related Experiment Video
Updated: Aug 14, 2026

09:09
A Modified Heterotopic Swine Hind Limb Transplant Model for Translational Vascularized Composite Allotransplantation (VCA) Research
Published on: October 14, 2013
Fasciocutaneous flaps: an experimental model in the pig
1Division of Plastic Surgery, Royal Victoria Hospital, Montreal, Quebec, Canada.
Plastic and Reconstructive Surgery
|January 1, 1989
Summary
Fasciocutaneous flaps demonstrated superior survival rates compared to skin flaps in a pig model, surviving 12-18% longer. Blood flow measurements did not show significant differences, suggesting other factors influence flap viability.
Area of Science:
- Plastic Surgery
- Surgical Research
- Biomedical Engineering
Background:
- The clinical superiority of fasciocutaneous flaps over skin flaps remains unsubstantiated by experimental data.
- Previous claims regarding fasciocutaneous flap advantages require rigorous scientific validation.
Purpose of the Study:
- To experimentally compare the survival rates and blood flow of fasciocutaneous flaps versus skin flaps.
- To investigate the underlying physiological differences contributing to flap viability.
Main Methods:
- Utilized pig models to create and assess forelimb and hindlimb fasciocutaneous and cutaneous flaps.
- Employed the radioactive microsphere technique for blood flow measurement post-flap elevation.
- Estimated flap survival using fluorescein viability assessment.
Main Results:
- Fasciocutaneous flaps exhibited statistically significant superior survival lengths (p < 0.01) compared to skin flaps.
- Forelimb and hindlimb fasciocutaneous flaps survived approximately 12-18% longer than their cutaneous counterparts.
- No significant differences in measured blood flow were detected between the two flap types.
Conclusions:
- Fasciocutaneous flaps show enhanced survival compared to skin flaps in this experimental model.
- The lack of difference in blood flow may be attributed to measurement intervals relative to survival differences.
- Further research is needed to elucidate the mechanisms behind improved fasciocutaneous flap survival.

