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[Chemical constituents from Murraya euchrestifolia].

Yue-Mei Chen1, Nan-Kai Cao1, Peng-Fei Tu1

  • 1State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.

Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica
|November 2, 2017
PubMed
Summary

This study isolated eighteen chemical compounds from Murraya euchrestifolia, identifying novel compounds and expanding knowledge of the Murraya genus

Keywords:
Murraya euchrestifoliachemical constituentscoumarinsflavonoidsphenylpropanoids

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Area of Science:

  • Phytochemistry
  • Natural Product Chemistry
  • Organic Chemistry

Background:

  • Murraya euchrestifolia is a plant species with potential medicinal properties.
  • Understanding its chemical constituents is crucial for pharmacological research.

Purpose of the Study:

  • To isolate and characterize the chemical compounds from Murraya euchrestifolia.
  • To identify novel compounds within the Murraya genus.

Main Methods:

  • Open silica gel, ODS, and Sephadex LH-20 column chromatography.
  • Semi-preparative High-Performance Liquid Chromatography (HPLC).
  • Structure elucidation using NMR, MS, and literature data.

Main Results:

  • Eighteen compounds were isolated from the dichloromethane fraction.
  • Compounds 1-15 and 18 were identified as new to the Murraya genus.
  • Compounds 16 and 17 were isolated from M. euchrestifolia for the first time.

Conclusions:

  • The study successfully identified a diverse range of chemical constituents from M. euchrestifolia.
  • This research contributes new natural products to the Murraya genus and provides a foundation for further investigation.