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Change of Helicobacter pylori prevalence in a decade among children undergoing endoscopy

Aytaç Yaman1, Zarife Kuloğlu1, Ahmet Kahveci2

  • 1Ankara University Faculy of Medicine, Pediatric Gastroenterology, Ankara, Turkey.

The Turkish Journal of Pediatrics
|November 2, 2017
PubMed

Insights

Helicobacter pylori (H. pylori) infection rates significantly decreased in children undergoing upper endoscopy in Ankara over a decade. This trend suggests a positive public health impact on pediatric H. pylori prevalence.

Area of Science:

  • Pediatric Gastroenterology
  • Infectious Diseases
  • Public Health

Background:

  • Helicobacter pylori (H. pylori) infection is a significant cause of gastritis and peptic ulcers in children.
  • Understanding trends in H. pylori prevalence is crucial for assessing the effectiveness of control strategies and informing clinical practice.
  • Previous studies have indicated varying H. pylori prevalence rates globally, with a need for region-specific data, particularly in pediatric populations.

Purpose of the Study:

  • To investigate the temporal trend of H. pylori infection in pediatric patients over a ten-year period.
  • To analyze the association between H. pylori infection and the prevalence of gastritis and atrophy in children.
  • To provide updated data on pediatric H. pylori prevalence in Ankara, Turkey.

Main Methods:

  • Retrospective analysis of esophagogastroduodenoscopy (EGD) reports from pediatric patients.
  • Patients were divided into two groups based on EGD performance: 2002-2003 (Group I) and 2012-2013 (Group II).
  • Pathology reports were reviewed for H. pylori presence, gastritis, and atrophy; statistical analysis compared prevalence between groups.

Main Results:

  • A total of 380 children were included (131 in Group I, 249 in Group II).
  • H. pylori positivity significantly decreased from 48.1% in Group I to 23.1% in Group II (p < 0.001).
  • Both gastritis and atrophy were significantly more prevalent in Group I and associated with H. pylori infection (p < 0.001).

Conclusions:

  • H. pylori prevalence has significantly decreased in the pediatric population undergoing EGD in Ankara over the past decade.
  • The observed decline may reflect improved sanitation, public health interventions, or changes in diagnostic practices.
  • This study provides the most current data on pediatric H. pylori prevalence trends in Turkey, highlighting a positive public health development.

Keywords:
H. pylori prevalencechildrenendoscopy

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