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Updated: Feb 11, 2026
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Diffusion Tensor Magnetic Resonance Imaging in Chronic Spinal Cord Compression
Published on: May 7, 2019
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Spinal cord compression in type I Gaucher disease
G Hermann1, L D Wagner, E S Gendal
1Department of Radiology, Mount Sinai Medical Center, New York, NY 10029-6574.
Radiology
|January 1, 1989
Summary
Spinal cord compression is a rare complication of Gaucher disease type I. Magnetic resonance (MR) imaging is a safe and accurate diagnostic tool for this condition.
Area of Science:
- Neurology
- Genetics
- Radiology
Background:
- Type I Gaucher disease can present with rare but serious complications.
- Epidural spinal cord compression is a significant concern in affected individuals.
Observation:
- Three patients with type I Gaucher disease and spinal cord compression were analyzed.
- Compression occurred in the thoracic region (T-11, T-12) due to vertebral collapse in two patients.
- One patient developed an epidural mass at T-2 with diffuse infiltration of T-2 and T-3.
Findings:
- Magnetic resonance (MR) imaging was utilized for diagnosis in two cases.
- MR imaging accurately demonstrated the nature and extent of the epidural disease.
- The imaging findings confirmed spinal cord compression as a complication of Gaucher disease.
Implications:
- Early and accurate diagnosis of spinal cord compression is crucial for managing Gaucher disease complications.
- MR imaging is a valuable tool for visualizing spinal canal pathology in Gaucher disease.
- Understanding these complications aids in developing comprehensive patient care strategies.
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