Related Experiment Video
Updated: Feb 19, 2026
Endovascular Perforation Model for Subarachnoid Hemorrhage Combined with Magnetic Resonance Imaging MRI
Published on: December 16, 2021
Simulated Effects of Perianeurysmal Bone on a Cerebral Aneurysm: A Case Study
Fuyu Wang1, Zhe Xue, Zhenghui Sun
1Chinese PLA General Hospital, Department of Neurosurgery, Beijing, China.
Aim:
To use computational models to explore the influence of contact with perianeurysmal bone on an intracranial aneurysm.
Material And Methods:
A middle cerebral artery aneurysm in contact with an anterior clinoid process was selected. Two anatomic models were constructed from computed tomography angiography images: A non-contact model with elasticity of the entire aneurysm wall and a contact model with rigidity of the part of the aneurysm wall contacting bone. The blood flow pattern, and wall stress and displacement were compared between the two models.
Results:
The contact and non-contact models exhibited similar wall shear stress and pressure, but different degrees of von Mises stress and wall displacement. Displacement close to the bone contact part of the aneurysm wall was less in the contact model than in the non-contact model, whereas displacement of the part opposite to the contact part was larger in the contact model than in the non-contact model. Also, von Mises stress close to the contact part was larger in the contact model than in the non-contact model.
Conclusion:
Contacting perianeurysmal bone affects the deformation and degree of von Mises stress but not the hemodynamics of intracranial aneurysms.
