Related Experiment Video

Updated: Jul 13, 2026

Intracranial Subarachnoidal Route of Infection for Investigating Roles of Streptococcus suis Biofilms in Meningitis in a Mouse Infection Model
07:26

Intracranial Subarachnoidal Route of Infection for Investigating Roles of Streptococcus suis Biofilms in Meningitis in a Mouse Infection Model

Published on: July 1, 2018

7.8K

A chinese case of prevotella intermedia and streptococcus constellatus intracranial mixed infection

Shanying Mo1, Liuhua Wei1, Hongmou Chen2

  • 1Medical Science Laboratory, the Fourth Affiliated Hospital of Guangxi Medical University, Liuzhou, Guangxi, China.

Metabolic Brain Disease
|November 3, 2017
PubMed

Insights

Brain infections from Streptococcus constellatus are rising. A rare case highlights the danger of mixed Prevotella intermedia and Streptococcus constellatus brain infections, emphasizing prompt diagnosis and broad-spectrum antibiotics.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Microbiology

Background:

  • Streptococcal species are an emerging cause of brain infections globally.
  • Streptococcus constellatus is a common pathogen, while anaerobic bacteria are rare causes of intracranial infection.

Observation:

  • This report details a rare case of intracranial mixed infection caused by Prevotella intermedia and Streptococcus constellatus in China.
  • The case highlights epidemiological risk factors, clinical features, and patient outcomes.

Findings:

  • Intracranial mixed infections involving Prevotella intermedia and Streptococcus constellatus have not been previously reported.
  • Fetid cerebrospinal fluid in exacerbated brain infections necessitates urgent, repeated imaging.

Implications:

  • Early and repeated neuroimaging is crucial for diagnosing severe brain infections.
  • Empiric antibiotic treatment should cover both anaerobic and aerobic bacteria in suspected mixed intracranial infections.
Keywords:
CTChinaIntracranial mixed infectionMRIPrevotella intermediaStreptococcus constellatus

More Related Videos

Concomitant Isolation of Primary Astrocytes and Microglia for Protozoa Parasite Infection09:34

Concomitant Isolation of Primary Astrocytes and Microglia for Protozoa Parasite Infection

Published on: March 18, 2020

8.2K
Conjunctival Commensal Isolation and Identification in Mice07:52

Conjunctival Commensal Isolation and Identification in Mice

Published on: May 1, 2021

5.0K

Related Concept Videos

Bacterial Meningitis01:24

Bacterial Meningitis

Bacterial meningitis is a severe infectious disease involving inflammation of the meninges, the protective membranes surrounding the brain and spinal cord. It occurs when pathogenic bacteria cross the blood–brain barrier and enter the cerebrospinal fluid. Common causative organisms include Neisseria meningitidis, Streptococcus pneumoniae, Haemophilus influenzae type b, Listeria monocytogenes, and Escherichia coli K1. The exact route of entry varies by pathogen and host condition.Routes of Entry...
Streptococcal Pharyngitis01:27

Streptococcal Pharyngitis

Streptococcal pharyngitis, commonly known as “strep throat,” is an acute infection of the oropharyngeal tissues caused by the Gram‑positive Group A Streptococcus (Streptococcus pyogenes). Transmission occurs primarily through respiratory droplets expelled during coughing, sneezing, or talking.Mechanisms of Host Entry and Immune EvasionUpon entering the host, S. pyogenes adheres to the mucosal epithelial cells of the pharynx via surface proteins, notably lipoteichoic acid and the antiphagocytic...
Viral Meningitis01:18

Viral Meningitis

Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...
Cryptococcal Meningitis01:27

Cryptococcal Meningitis

Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...
Bacterial Meningitis I: Introduction01:22

Bacterial Meningitis I: Introduction

Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
Brain Abscess l: Introduction01:26

Brain Abscess l: Introduction

A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...