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Published on: June 8, 2022
Treatment of prosthetic valve endocarditis by aortic valve neocuspidization using bovine pericardium
Yasunori Iida1, Kazuma Shimura1, Sho Akiyama1
1Department of Cardiovascular Surgery, Ogikubo Hospital, Tokyo, Japan.
Abstract:
A 78-year-old man who had undergone aortic valve and ascending aorta replacements presented with fever and was referred to our hospital. Blood culture revealed Gram-positive cocci, thus antibiotic therapy was started. Brain magnetic resonance imaging showed fresh cerebral infarction without cerebral haemorrhage or mycotic aneurysm. Transoesophageal echocardiogram revealed a vegetation that was attached to the right coronary cusp. The patient underwent successful aortic valve neocuspidization using glutaraldehyde-treated bovine pericardium. The postoperative course was uneventful with intravenous antibiotics administered for 6 weeks after confirming a negative blood culture, and no cardiac events occurred on follow-up by transthoracic echocardiogram 14 months postoperatively.
Insights
A 78-year-old man with a history of aortic valve replacement developed fever and neurological symptoms. He was successfully treated with aortic valve neocuspidization and antibiotics for infective endocarditis.
Area of Science:
- Cardiology
- Infectious Diseases
- Cardiac Surgery
Background:
- Infective endocarditis is a serious complication following cardiac surgery.
- Prosthetic valve endocarditis requires prompt diagnosis and management.
- Cerebral infarction can be a manifestation of infective endocarditis.
Observation:
- A 78-year-old male with prior aortic valve and ascending aorta replacement presented with fever and neurological deficits.
- Blood cultures identified Gram-positive cocci, and imaging revealed cerebral infarction and a vegetation on the aortic valve.
- Transesophageal echocardiogram confirmed a vegetation on the right coronary cusp.
Findings:
- The patient underwent successful aortic valve neocuspidization using glutaraldehyde-treated bovine pericardium.
- Postoperative treatment included 6 weeks of intravenous antibiotics.
- Follow-up demonstrated no cardiac events and negative blood cultures.
Implications:
- Aortic valve neocuspidization is a viable option for managing prosthetic valve endocarditis.
- Early diagnosis and aggressive treatment are crucial for favorable outcomes.
- This case highlights the importance of considering infective endocarditis in patients with prosthetic valves presenting with systemic symptoms.
Related Concept Videos
Endocarditis III: Medical Management
Endocarditis I: Introduction
Endocarditis IV: Nursing Management
Endocarditis II: Clinical Features of Infective Endocarditis
Mitral Stenosis III: Medical Management
Pericarditis III: Medical Management

