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Fully nozzle-jet printed non-enzymatic electrode for biosensing application.

Kiesar Sideeq Bhat1, Rafiq Ahmad1, Jin-Young Yoo1

  • 1School of Semiconductor and Chemical Engineering, Nanomaterials Processing, Research Center, Chonbuk National University, 567 Baekjedaero, Deokjin-gu, Jeonju-si, Jeollabuk-do 54896, Republic of Korea.

Journal of Colloid and Interface Science
|November 3, 2017
PubMed
Summary

We developed a novel, facile method for creating electrochemical sensors using nozzle-jet printing. This technique enables the fabrication of highly sensitive and stable non-enzymatic glucose biosensors on flexible substrates.

Keywords:
Glucose biosensorLong term stabilityNon-enzymaticNozzle-jet printing

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Area of Science:

  • Electrochemistry
  • Materials Science
  • Biosensor Technology

Background:

  • Advancements in electrochemical sensors for biomolecule detection necessitate simplified fabrication methods.
  • Flexible electronic devices offer new possibilities for point-of-care diagnostics.

Purpose of the Study:

  • To report a facile fabrication method for non-enzymatic glucose biosensors using nozzle-jet printing.
  • To develop a high-performance glucose biosensor on a flexible substrate.

Main Methods:

  • Fabrication of silver (Ag) precursor and copper oxide nanoparticles (CuO NPs) inks.
  • Nozzle-jet printing of inks onto a flexible polyethylene terephthalate (PET) substrate to create CuO NPs/Ag/PET electrodes.
  • Electrochemical characterization of the printed electrodes for non-enzymatic glucose sensing.

Main Results:

  • The printed non-enzymatic biosensor achieved high sensitivity (1424.2 μA mM⁻¹ cm⁻²), a linear range of 0.1–15 mM, and a low detection limit (0.3 μM).
  • The sensor demonstrated a fast response time (∼2 s) at a working potential of +0.6 V.
  • The printed electrodes exhibited excellent long-term stability, reproducibility, selectivity, and accuracy in human blood and serum samples.

Conclusions:

  • Nozzle-jet printing is a viable technique for fabricating high-performance, low-cost bio/chemical sensor devices.
  • The developed printed electrodes show significant potential for future applications in glucose monitoring and diagnostics.