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Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
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Evaluation of Cognitive Function Following Transcatheter Aortic Valve Replacement
Masieh Abawi1, Rehana de Vries2, Pieter R Stella1
1Department of Cardiology, University Medical Center Utrecht, The Netherlands.
Heart, Lung & Circulation
|November 4, 2017
Summary
Transcatheter aortic valve replacement (TAVR) improved immediate recall memory test scores at four months. Patients with lower baseline cognitive function showed the most significant cognitive improvements after TAVR.
Area of Science:
- Cardiology
- Neurology
- Gerontology
Background:
- Transcatheter aortic valve replacement (TAVR) is linked to neurological issues and acute cognitive decline.
- Limited data exists on the mid-term cognitive effects of TAVR.
- This study investigates TAVR's impact on mid-term cognitive function.
Purpose of the Study:
- To evaluate the mid-term cognitive outcomes following TAVR.
- To assess changes in memory, global cognitive function, and executive function post-TAVR.
Main Methods:
- 30 patients with severe aortic valve stenosis undergoing TAVR were enrolled.
- Cognitive assessments included verbal learning tests (IRMT, DRMT, RVIT), MMSE, and executive function tests (TMT, CDT).
- Assessments were conducted at baseline and 4 months post-TAVR.
Main Results:
- A significant improvement in the Immediate Recall Memory Test (IRMT) was observed at 4 months (p=0.016).
- A trend towards improved Delayed Recall Memory Test (DRMT) scores was noted (p=0.079).
- Patients with lower baseline MMSE and IRMT scores demonstrated significant cognitive improvements.
Conclusions:
- TAVR was associated with improved IRMT scores at mid-term follow-up.
- Cognitive benefits were more pronounced in patients with lower baseline cognitive function.
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