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Published on: August 30, 2020
Case of Subarachnoid Hemorrhage Caused by Tuberculous Aneurysm
Wei Liu1, Chuanfeng Li2, Xianming Liu2
1Department of Neurosurgery, Affiliated Hospital of Qingdao University, Qingdao, China.
Background:
Subarachnoid hemorrhage caused by rupture of tuberculosis associated aneurysm is a rare complication. In this paper, we report a case of intracranial tuberculum with adjacent intracerebral inflammatory aneurysm which caused subarachnoid hemorrhage and brain abscess formation.
Case Description:
A 28-year-old man presented with sudden onset of severe headache. He was diagnosed with pulmonary tuberculosis 8 years ago, and had been treated with antituberculosis medications for 6 months. Head computed tomography showed a small hematoma in the left sylvian fissure with subarachnoid hemorrhage. Cerebral digital subtraction angiography was performed and no aneurysm was found. He was discharged after nonsurgical treatment. Three weeks later, he came back to our department with complaint of aphasia. Magnetic resonance images showed a cystic lesion with mass effect. During operation, we encounter the brain abscess and were surprised to find a middle cerebral artery aneurysm while dissecting. The abscess was totally removed, and the aneurysm was secured by clipping. The aneurysm was suspected of being inflammatory in nature and associated with the patient's tuberculosis.
Conclusions:
Tuberculosis in the central nervous system may present as tuberculoma and tuberculous meningitis. Vasculitis secondary to tuberculous meningitis can cause infarcts, and, rarely, aneurysm formation. This case report illustrated a rare case of intracranial infectious aneurysm related to tuberculosis and complicated by hemorrhage and brain abscess.
Insights
Ruptured tuberculosis-associated aneurysms are rare. This case highlights an intracranial tuberculum with an adjacent inflammatory aneurysm causing subarachnoid hemorrhage and brain abscess.
Area of Science:
- Neurology
- Infectious Diseases
- Neurosurgery
Background:
- Tuberculosis can affect the central nervous system, leading to complications like tuberculomas and meningitis.
- Tuberculous meningitis can cause vasculitis, potentially resulting in aneurysms, though this is rare.
Observation:
- A 28-year-old man with a history of pulmonary tuberculosis presented with subarachnoid hemorrhage.
- Initial imaging revealed a hematoma, but no aneurysm was detected.
- Follow-up imaging showed a brain abscess, and surgery revealed an associated middle cerebral artery aneurysm.
Findings:
- The case describes a rare instance of an intracranial infectious aneurysm linked to tuberculosis.
- The aneurysm was associated with a brain abscess and caused subarachnoid hemorrhage.
- The aneurysm was suspected to be inflammatory due to its association with tuberculosis.
Implications:
- This case underscores the importance of considering tuberculosis as a potential cause of intracranial aneurysms, even in the absence of meningitis.
- Early diagnosis and treatment of CNS tuberculosis are crucial to prevent rare but severe vascular complications.
- Management involves addressing both the infectious and vascular components, including abscess drainage and aneurysm repair.
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