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Related Experiment Video

Updated: Feb 19, 2026

Design and Implementation of an fMRI Study Examining Thought Suppression in Young Women with, and At-risk, for Depression
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Preventing Depression in Final Year Secondary Students: School-Based Randomized Controlled Trial.

Yael Perry1, Aliza Werner-Seidler1, Alison Calear2

  • 1Black Dog Institute, University of New South Wales, Randwick, Australia.

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|November 4, 2017
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Summary
This summary is machine-generated.

This study found that the SPARX-R online program effectively reduced depression symptoms in adolescents before final exams. The intervention showed lasting benefits up to six months post-treatment, highlighting its potential for preventing adolescent depression.

Keywords:
adolescentdepressiondigital cognitive behavior therapyprevention

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Area of Science:

  • Adolescent mental health
  • Clinical psychology
  • Digital health interventions

Background:

  • Adolescence is a critical period for the onset of depression.
  • School-based universal depression prevention programs show promise.
  • Early intervention is key to mitigating depressive symptoms.

Purpose of the Study:

  • To evaluate the effectiveness of SPARX-R, a gamified online cognitive behavior therapy (CBT) intervention.
  • To assess depression prevention in adolescents facing significant stressors (final secondary school exams).
  • To test the hypothesis that pre-stressor intervention reduces depressive symptoms.

Main Methods:

  • Cluster randomized controlled trial in 10 Australian secondary schools.
  • 540 final year students participated, randomized to SPARX-R or control.
  • Intervention involved 7 weekly online modules; depression measured by Major Depression Inventory.

Main Results:

  • SPARX-R significantly reduced depression symptoms compared to controls post-intervention (Cohen d=0.29).
  • Benefits were sustained at 6 months (d=0.21) but not at 18 months (d=0.33).
  • Effect sizes indicate a small to moderate preventive impact.

Conclusions:

  • First trial demonstrating preventive effects on adolescent depression before a major stressor.
  • Online interventions delivered proactively can lessen depression's impact.
  • SPARX-R offers a viable tool for school-based adolescent depression prevention.