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High-grade myofibroblastic sarcoma in the liver: A case report
Jun Wen1, Wei Zhao2, Chuan Li1
1Department of Liver Surgery and Liver Transplantation Center, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China.
World Journal of Gastroenterology
|November 4, 2017
Summary
This report details a rare high-grade myofibroblastic sarcoma in a male patient's liver, initially misdiagnosed as echinococcosis. The successful surgical resection highlights a critical diagnostic consideration for liver masses.
Area of Science:
- Hepatobiliary pathology
- Surgical oncology
- Rare tumor diagnosis
Background:
- Myofibroblastic sarcoma is an uncommon malignancy with limited reported cases in the liver.
- Accurate diagnosis is crucial for appropriate patient management and treatment strategies.
Observation:
- A 25-year-old male presented with right upper quadrant pain, initially suspected to be echinococcosis.
- A large liver mass (over 16 cm) was discovered during exploratory laparotomy and surgically resected.
- Histopathological and immunohistochemical analysis confirmed high-grade myofibroblastic sarcoma.
Findings:
- The tumor exhibited positive staining for desmin, α-smooth muscle actin, CD56, and vimentin.
- The Ki-67 proliferation index was approximately 20%.
- This case represents the first reported instance of high-grade myofibroblastic sarcoma in the liver of a male patient.
Implications:
- This case expands the understanding of myofibroblastic sarcoma presentation and diagnosis in the liver.
- Highlights the importance of considering rare differentials in liver mass diagnosis.
- Suggests potential for successful surgical management without adjuvant therapy in select cases.
