Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cardiomyopathy VII: Pre and Post Operative Nursing Management01:28

Cardiomyopathy VII: Pre and Post Operative Nursing Management

386
Patients with hypertrophic cardiomyopathy (HCM) and left ventricular outflow tract (LVOT) obstruction who remain symptomatic despite optimal medical therapy may undergo a septal myectomy (Morrow procedure). This procedure involves excising a portion of the hypertrophied septum below the aortic valve using a heart-lung machine to improve blood flow through the LVOT. Effective preoperative and postoperative nursing management ensures successful patient outcomes, minimizes complications, and...
386
Aneurysm IV: Nursing Management01:22

Aneurysm IV: Nursing Management

491
Vigilant monitoring for aneurysm rupture is essential for patients undergoing aortic surgery.Preoperative Nursing ManagementContinuously monitor the patient for manifestations of aneurysm rupture, such as pallor, weakness, tachycardia, hypotension, abdominal, back, groin, or periumbilical pain, changes in consciousness, and a pulsating abdominal mass. Regularly assess the patient's peripheral pulses.Instruct the patient to consume a clear liquid diet the day before surgery and administer...
491
Esophageal Varices-II: Clinical Features and Management01:28

Esophageal Varices-II: Clinical Features and Management

647
Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
647
Peripheral Artery Disease V: Postoperative Nursing Management01:23

Peripheral Artery Disease V: Postoperative Nursing Management

431
During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
431
Disorders of Hemostasis01:24

Disorders of Hemostasis

2.4K
Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
2.4K
Cardiac Catheterization II: Right Heart Catheterization01:21

Cardiac Catheterization II: Right Heart Catheterization

1.2K
Right Heart Catheterization: An OverviewRight heart catheterization is an invasive diagnostic procedure that measures right-sided cardiac and pulmonary artery pressures, calculates cardiac output, and identifies intracardiac shunts. It provides detailed hemodynamic data essential for diagnosing and managing various cardiovascular conditions, such as pulmonary hypertension.Access SitesCommon access sites for right heart catheterization include the internal jugular vein in the neck region, the...
1.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Thiazolidinsone derivatives bearing sulfonamide group as potential antimicrobial agents: biological and in silico evaluation.

SAR and QSAR in environmental research·2025
Same author

Anti-inflammatory action of new hybrid <i>N</i>-acyl-[1,2]dithiolo-[3,4-<i>c</i>]quinoline-1-thione.

SAR and QSAR in environmental research·2024
Same author

Steroidal hydrazones as antimicrobial agents: biological evaluation and molecular docking studies.

SAR and QSAR in environmental research·2024
Same author

Functionally substituted 2-aminothiazoles as antimicrobial agents: in vitro and in silico evaluation.

SAR and QSAR in environmental research·2023
Same author

Discovery of benzothiazole-based thiazolidinones as potential anti-inflammatory agents: anti-inflammatory activity, soybean lipoxygenase inhibition effect and molecular docking studies.

SAR and QSAR in environmental research·2022
Same author

Caffeic and 3-(3,4-dihydroxyphenyl)glyceric acid derivatives as antimicrobial agent: biological evaluation and molecular docking studies.

SAR and QSAR in environmental research·2022

Related Experiment Video

Updated: Feb 19, 2026

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock
06:10

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock

Published on: June 12, 2021

3.7K

Massive bleeding in cardiac surgery. Definitions, predictors and challenges.

A Petrou1, P Tzimas1, S Siminelakis2

  • 1Department of Anesthesiology and Postoperative Intensive Care, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, Hellas.

Hippokratia
|November 4, 2017
PubMed
Summary

Severe bleeding in cardiac surgery is a serious issue with diverse definitions. A unified definition is needed to improve prediction, management, and patient outcomes in massive hemorrhage cases.

Keywords:
Massive bleedingadultcardiac surgerymassive transfusionsevere bleeding

More Related Videos

Complete and Partial Aortic Occlusion for the Treatment of Hemorrhagic Shock in Swine
09:37

Complete and Partial Aortic Occlusion for the Treatment of Hemorrhagic Shock in Swine

Published on: August 24, 2018

11.0K
Author Spotlight: Enhancing Coronary Artery Revascularization
05:25

Author Spotlight: Enhancing Coronary Artery Revascularization

Published on: September 15, 2023

1.3K

Related Experiment Videos

Last Updated: Feb 19, 2026

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock
06:10

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock

Published on: June 12, 2021

3.7K
Complete and Partial Aortic Occlusion for the Treatment of Hemorrhagic Shock in Swine
09:37

Complete and Partial Aortic Occlusion for the Treatment of Hemorrhagic Shock in Swine

Published on: August 24, 2018

11.0K
Author Spotlight: Enhancing Coronary Artery Revascularization
05:25

Author Spotlight: Enhancing Coronary Artery Revascularization

Published on: September 15, 2023

1.3K

Area of Science:

  • Cardiovascular Surgery
  • Hemorrhage Management
  • Transfusion Medicine

Background:

  • Severe or massive bleeding is an uncommon yet critical complication in cardiac surgery.
  • Existing definitions of severe hemorrhage are inconsistent and challenging to apply during active bleeding.
  • The characteristics of hemorrhage evolve, complicating accurate and timely definition.

Purpose of the Study:

  • To review the definition and grading of severe hemorrhage and massive transfusion in cardiac surgery.
  • To identify predictors of bleeding and transfusion-related mortality.
  • To describe risks of re-exploration and economic impacts of severe bleeding.

Main Methods:

  • A narrative, non-systematic literature review was conducted.
  • The review focused on clinical questions regarding hemorrhage definition, grading, and transfusion.
  • Data retrieval aimed to identify mortality predictors and associated risks.

Main Results:

  • Massive perioperative bleeding is characterized by bleeding rate, extent, and transfusion volume.
  • Severe bleeding significantly impacts mortality, logistics, and hospital finances.
  • Patient comorbidities, bleeding severity, and transfusion volume predict mortality; re-exploration is a hazardous adverse event.

Conclusions:

  • Severe perioperative hemorrhage in cardiac surgery is associated with substantial morbidity and mortality.
  • Predicting and identifying massive bleeding is feasible but incomplete.
  • A comprehensive definition of massive perioperative bleeding is needed to enhance preparedness and management protocols.