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Updated: Sep 12, 2026
Depletion and Reconstitution of Macrophages in Mice
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Activation of mouse peritoneal macrophages by mannophosphoinositides of mycobacteria
1Department of Biochemistry, Postgraduate Institute of Medical Education and Research, Changigarh, India.
Abstract:
Peritoneal macrophages isolated from mannoside-methylated bovine serum albumin (MBSA)-immunized mice showed significantly enhanced phagocytosis of Mycobacterium smegmatis compared to control or MBSA-immunized groups. Immune macrophages also exhibited bacteriostatic activity against M. smegmatis. Pretreatment of mycobacteria with mannoside antibodies did not further alter the phagocytosis and bacteriostatic effect of immune macrophages.
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