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Updated: Feb 19, 2026

Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction
Published on: February 13, 2021
Utility intervention programs in the evolutional control of patients with heart failure
Álvaro Flamarique-Pascual1, Eduardo Esteban-Zubero2, Francisco José Ruiz-Ruiz1
1Departamento de Medicina, Psiquiatría y Dermatología.
Close monitoring of patients with heart failure (HF) significantly improves treatment adherence and survival rates. This intervention strategy also reduces mortality, leading to potential socio-economic benefits in healthcare.
Area of Science:
- Cardiology
- Public Health
- Health Economics
Background:
- Acute heart failure (HF) is a widespread condition with significant socio-economic impacts.
- Population aging is projected to increase HF prevalence and associated healthcare demands.
- Effective intervention programs are crucial for reducing HF morbidity and mortality.
Purpose of the Study:
- To evaluate the impact of an intensive intervention program on patients with acute heart failure.
- To compare therapeutic adherence and clinical outcomes between an intervention group and a historical control group.
- To assess the socio-economic benefits of improved HF management.
Main Methods:
- A quasi-experimental prospective study involving 262 patients diagnosed with HF.
- Comparison between a historical cohort (n=154) and a prospective group (n=108) with a subgroup (n=30) receiving intensive intervention.
- Data collection included adherence to clinical guidelines, mortality rates, and survival over a 1-year follow-up period.
Main Results:
- Statistically significant differences were observed in adherence to clinical guidelines (p < 0.011) between the groups.
- The intensive intervention subgroup showed significant differences in mortality rate (p < 0.032) and survival (log rank <0.030) compared to the control group.
- Close patient monitoring enhanced adherence, reduced mortality, and improved survival.
Conclusions:
- Intensive monitoring and intervention programs for heart failure patients improve adherence and survival.
- These programs can lead to reduced mortality and better patient outcomes.
- Improved HF management offers significant socio-economic benefits through decreased healthcare resource utilization.
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