Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Reduction of Alkenes: Asymmetric Catalytic Hydrogenation02:17

Reduction of Alkenes: Asymmetric Catalytic Hydrogenation

3.9K
Catalytic hydrogenation of alkenes is a transition-metal catalyzed reduction of the double bond using molecular hydrogen to give alkanes. The mode of hydrogen addition follows syn stereochemistry.
The metal catalyst used can be either heterogeneous or homogeneous. When hydrogenation of an alkene generates a chiral center, a pair of enantiomeric products is expected to form. However, an enantiomeric excess of one of the products can be facilitated using an enantioselective reaction or an...
3.9K
Reduction of Alkenes: Catalytic Hydrogenation02:13

Reduction of Alkenes: Catalytic Hydrogenation

14.5K
Alkenes undergo reduction by the addition of molecular hydrogen to give alkanes. Because the process generally occurs in the presence of a transition-metal catalyst, the reaction is called catalytic hydrogenation.
Metals like palladium, platinum, and nickel are commonly used in their solid forms — fine powder on an inert surface. As these catalysts remain insoluble in the reaction mixture, they are referred to as heterogeneous catalysts.
The hydrogenation process takes place on the...
14.5K
Reduction of Alkynes to cis-Alkenes: Catalytic Hydrogenation02:24

Reduction of Alkynes to cis-Alkenes: Catalytic Hydrogenation

9.1K
Introduction
Like alkenes, alkynes can be reduced to alkanes in the presence of transition metal catalysts such as Pt, Pd, or Ni. The reaction involves two sequential syn additions of hydrogen via a cis-alkene intermediate.
9.1K
Reduction of Benzene to Cyclohexane: Catalytic Hydrogenation01:28

Reduction of Benzene to Cyclohexane: Catalytic Hydrogenation

6.0K
Unlike the easy catalytic hydrogenation of an alkene double bond, hydrogenation of a benzene double bond under similar reaction conditions does not take place easily. For example, in the reduction of stilbene, the benzene ring remains unaffected while the alkene bond gets reduced. Hydrogenation of an alkene double bond is exothermic and a favorable process. In contrast, to hydrogenate the first unsaturated bond of benzene, an energy input is needed; that is, the process is endothermic. This is...
6.0K
Catalysis02:50

Catalysis

30.9K
The presence of a catalyst affects the rate of a chemical reaction. A catalyst is a substance that can increase the reaction rate without being consumed during the process. A basic comprehension of a catalysts’ role during chemical reactions can be understood from the concept of reaction mechanisms and energy diagrams.
30.9K
Regioselectivity of Electrophilic Additions to Alkenes: Markovnikov's Rule02:17

Regioselectivity of Electrophilic Additions to Alkenes: Markovnikov's Rule

17.6K
If a set of reactants can yield multiple constitutional isomers, but one of the isomers is obtained as the major product, the reaction is said to be regioselective. In such reactions, bond formation or breaking is favored at one reaction site over others.
The hydrohalogenation of an unsymmetrical alkene can yield two haloalkane products, depending on which vinylic carbon takes up the halogen. However, one product usually predominates, where hydrogen adds to the vinylic carbon bearing the...
17.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

An Enhanced Particle Swarm Optimized RBF Model for Precise Fish Population Estimation in Cage Farming.

Animals : an open access journal from MDPI·2026
Same author

Assembly and comparative analysis of the complete mitochondrial genome of the endangered plant Fraxinus mandshurica.

BMC plant biology·2026
Same author

Creation of an air-stable surface electrene and its application to ammonia synthesis.

Nature communications·2026
Same author

Electron-rich dianion vacancies boost diazenide intermediates for efficient chemical looping ammonia synthesis.

Nature communications·2026
Same author

Comparison of the predictive value of mri-based cervical endplate bone quality (C-EBQ) score and cervical vertebral bone quality (C-VBQ) score for the progression of cervical disc degeneration.

European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·2026
Same author

Mo-Catalyzed Direct Nitrogen-to-Amine Conversion in Flow via Active N-H Species.

Journal of the American Chemical Society·2026

Related Experiment Video

Updated: Feb 19, 2026

Synthesis and Testing of Supported Pt-Cu Solid Solution Nanoparticle Catalysts for Propane Dehydrogenation
10:19

Synthesis and Testing of Supported Pt-Cu Solid Solution Nanoparticle Catalysts for Propane Dehydrogenation

Published on: July 18, 2017

12.6K

Copper-Based Intermetallic Electride Catalyst for Chemoselective Hydrogenation Reactions.

Tian-Nan Ye1,2, Yangfan Lu1,2, Jiang Li1,2

  • 1Materials Research Center for Element Strategy, Tokyo Institute of Technology , 4259 Nagatsuta, Midori-ku, Yokohama 226-8503, Japan.

Journal of the American Chemical Society
|November 4, 2017
PubMed
Summary

A novel copper-based intermetallic electride catalyst, LaCu0.67Si1.33, significantly enhances nitroarene hydrogenation. This catalyst exhibits superior activity and stability compared to traditional metal catalysts due to its unique electronic properties.

More Related Videos

Catalytic Reactions at Amine-Stabilized and Ligand-Free Platinum Nanoparticles Supported on Titania During Hydrogenation of Alkenes and Aldehydes
12:08

Catalytic Reactions at Amine-Stabilized and Ligand-Free Platinum Nanoparticles Supported on Titania During Hydrogenation of Alkenes and Aldehydes

Published on: June 24, 2022

4.1K
[DPEPhosbcpCu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst
09:12

[DPEPhosbcpCu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst

Published on: May 21, 2019

9.9K

Related Experiment Videos

Last Updated: Feb 19, 2026

Synthesis and Testing of Supported Pt-Cu Solid Solution Nanoparticle Catalysts for Propane Dehydrogenation
10:19

Synthesis and Testing of Supported Pt-Cu Solid Solution Nanoparticle Catalysts for Propane Dehydrogenation

Published on: July 18, 2017

12.6K
Catalytic Reactions at Amine-Stabilized and Ligand-Free Platinum Nanoparticles Supported on Titania During Hydrogenation of Alkenes and Aldehydes
12:08

Catalytic Reactions at Amine-Stabilized and Ligand-Free Platinum Nanoparticles Supported on Titania During Hydrogenation of Alkenes and Aldehydes

Published on: June 24, 2022

4.1K
[DPEPhosbcpCu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst
09:12

[DPEPhosbcpCu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst

Published on: May 21, 2019

9.9K

Area of Science:

  • Materials Science
  • Catalysis
  • Surface Chemistry

Background:

  • Transition metal intermetallic compounds offer tunable structures for enhanced catalysis.
  • Incorporating active sites within lattice frameworks modulates electronic properties and catalytic performance.

Purpose of the Study:

  • To develop a novel copper-based intermetallic electride catalyst for selective hydrogenation.
  • To investigate the catalytic activity, selectivity, and stability of the new material.

Main Methods:

  • Synthesis and characterization of the LaCu0.67Si1.33 intermetallic electride.
  • Evaluation of catalytic performance in nitroarene hydrogenation.
  • Kinetic analysis using isotope effects to determine the rate-determining step.

Main Results:

  • LaCu0.67Si1.33 demonstrates over 40-times higher turnover frequencies (up to 5084 h-1) for nitroarene hydrogenation compared to metal-loaded catalysts.
  • The catalyst exhibits a low activation energy (14.8 kJ·mol-1) for hydrogen activation due to high carrier density and low work function.
  • High chemoselectivity is achieved through preferential adsorption of nitroarenes via the nitro group, facilitated by the catalyst's oxygen affinity.

Conclusions:

  • The LaCu0.67Si1.33 electride catalyst surpasses conventional metal-loaded catalysts in activity and stability for nitroarene hydrogenation.
  • The unique lattice framework and electronic properties of the intermetallic compound are crucial for its enhanced catalytic function.
  • This work highlights the potential of transition metals integrated into specific lattice sites as highly efficient catalytic centers.