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Subclinical ventricular dysfunction by Speckle Tracking in adult patients with coarctation of the aorta

Nilda Espinola-Zavaleta1, José Carlos Rúan-Díaz1, María Elena Soto2

  • 1Laboratorio de Ecocardiografía y Hemodinámica no-invasiva, Instituto Nacional de Cardiología Ignacio Chávez, Ciudad de México, México.

Gaceta Medica De Mexico
|November 4, 2017
PubMed

Insights

Adult patients with aortic coarctation and systemic hypertension show subclinical left ventricular dysfunction. Key measures like global longitudinal deformation and left ventricular mass index are vital for timely therapeutic interventions.

Area of Science:

  • Cardiology
  • Echocardiography
  • Cardiovascular Imaging

Background:

  • Aortic coarctation (AoCo) is a congenital heart defect often associated with systemic arterial hypertension (SAH).
  • Early detection of left ventricular (LV) systolic dysfunction is crucial for managing patients with AoCo and SAH.
  • Speckle tracking echocardiography offers advanced methods for assessing LV function.

Purpose of the Study:

  • To investigate early left ventricular systolic dysfunction in adult patients with AoCo and SAH.
  • To compare LV function in patients with AoCo and SAH against hypertensive patients without AoCo and healthy controls.
  • To utilize speckle tracking to identify subclinical LV dysfunction.

Main Methods:

  • Study included 61 consecutive outpatients.
  • Methods involved clinical history, electrocardiogram, conventional echocardiogram, and speckle tracking echocardiography.
  • Patients were categorized into groups: AoCo with SAH, SAH only, and healthy controls.

Main Results:

  • A significant inverse correlation was found between global longitudinal deformation and LV mass index in both AoCo and SAH patients (r=0.53, p=0.02) and hypertensive patients (r=0.52, p<0.0001).
  • 15 patients with AoCo and SAH were in NYHA functional class I, and five were in class II.
  • Speckle tracking revealed significant relationships between deformation parameters and LV mass index.

Conclusions:

  • Global longitudinal deformation and LV mass index are significantly related to subclinical LV dysfunction in patients with AoCo and SAH.
  • These echocardiographic parameters are important indicators for timely therapeutic adjustments.
  • Early identification of subclinical dysfunction aids in managing cardiovascular risk in this population.
Abstract

Keywords:
Coarctation of the aortaEchocardiographyLongitudinal deformationRadial deformationSpeckle Tracking

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