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Colonic strictures in children and young adults with Crohn's disease: Recognition on MR enterography

David M Biko1, Petar Mamula2, Nancy A Chauvin1

  • 1Department of Radiology, The Children's Hospital of Philadelphia, Philadelphia, PA, United States; University of Pennsylvania School of Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA, United States.

Clinical Imaging
|November 4, 2017
PubMed
Abstract

Insights

Magnetic resonance enterography (MRE) can identify colonic strictures in Crohn's disease. MRE findings showed high concordance with surgical results for strictures in pediatric and young adult patients.

Area of Science:

  • Gastroenterology
  • Radiology
  • Pediatric Surgery

Background:

  • Crohn's disease frequently affects the colon, often leading to strictures.
  • Accurate identification of colonic strictures is crucial for management.
  • Magnetic resonance enterography (MRE) is a non-invasive imaging modality.

Purpose of the Study:

  • To identify features of colonic strictures using MRE in pediatric and young adult patients with Crohn's disease.
  • To evaluate the diagnostic performance of MRE for colonic strictures.

Main Methods:

  • Retrospective review of patients with colonic strictures diagnosed by colonoscopy and imaged with MRE.
  • Evaluation of MRE features including bowel wall thickening (BWT), luminal narrowing, pre-stenotic dilatation (PSD), bowel wall enhancement, and diffusion restriction.

Main Results:

  • All 12 patients with potential strictures demonstrated BWT with luminal narrowing on MRE.
  • Eight of 12 patients had PSD, meeting MRE criteria for strictures.
  • MRE diagnosed 8/12 colonic strictures, with concordance in all surgically confirmed cases.

Conclusions:

  • MRE demonstrates key features of colonic strictures in pediatric and young adult Crohn's disease patients.
  • MRE findings showed high concordance with surgical outcomes, suggesting its utility in evaluating colonic strictures.

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