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A program to calculate sample size, power, and least detectable relative risk using a programmable calculator
1Department of Epidemiology, School of Public Health and Community Medicine, University of Washington, Seattle 98195.
American Journal of Epidemiology
|January 1, 1989
Summary
This study presents a calculator program for determining sample size, statistical power, and minimum detectable relative risk in comparative studies. It supports various case-control and cohort study designs with flexible subject ratios.
Area of Science:
- Biostatistics
- Epidemiology
- Health Research Methods
Background:
- Comparative studies are essential for evaluating health interventions and risk factors.
- Accurate sample size and power calculations are crucial for study validity.
- Existing tools may lack flexibility for diverse study designs.
Purpose of the Study:
- To introduce a programmable calculator application for key epidemiological study parameters.
- To provide a flexible tool for sample size, power, and relative risk calculations.
- To facilitate research design in case-control and cohort studies.
Main Methods:
- Development of a program for the Hewlett Packard 41 series calculator.
- Implementation of algorithms for sample size, power, and least detectable relative risk.
- Inclusion of user-defined options for subject ratios and study types.
Main Results:
- The program successfully calculates sample size, power, and least detectable relative risk.
- User can specify case-control or cohort study designs.
- Flexible input for ratios of cases to controls or exposed to unexposed subjects.
Conclusions:
- The calculator program offers a practical tool for researchers designing comparative studies.
- It enhances the ability to plan studies with specific statistical requirements.
- This facilitates more robust epidemiological research through precise study design.