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A program to calculate sample size, power, and least detectable relative risk using a programmable calculator.

J M Muhm1, A F Olshan

  • 1Department of Epidemiology, School of Public Health and Community Medicine, University of Washington, Seattle 98195.

American Journal of Epidemiology
|January 1, 1989
PubMed
Summary

This study presents a calculator program for determining sample size, statistical power, and minimum detectable relative risk in comparative studies. It supports various case-control and cohort study designs with flexible subject ratios.

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Area of Science:

  • Biostatistics
  • Epidemiology
  • Health Research Methods

Background:

  • Comparative studies are essential for evaluating health interventions and risk factors.
  • Accurate sample size and power calculations are crucial for study validity.
  • Existing tools may lack flexibility for diverse study designs.

Purpose of the Study:

  • To introduce a programmable calculator application for key epidemiological study parameters.
  • To provide a flexible tool for sample size, power, and relative risk calculations.
  • To facilitate research design in case-control and cohort studies.

Main Methods:

  • Development of a program for the Hewlett Packard 41 series calculator.
  • Implementation of algorithms for sample size, power, and least detectable relative risk.

Related Experiment Videos

  • Inclusion of user-defined options for subject ratios and study types.

    • Main Results:

    • The program successfully calculates sample size, power, and least detectable relative risk.
    • User can specify case-control or cohort study designs.
    • Flexible input for ratios of cases to controls or exposed to unexposed subjects.

    Conclusions:

    • The calculator program offers a practical tool for researchers designing comparative studies.
    • It enhances the ability to plan studies with specific statistical requirements.
    • This facilitates more robust epidemiological research through precise study design.