Urinary tract aspergillosis in a patient with chronic kidney disease

Area of Science:

• Mycology
• Infectious Diseases
• Nephrology

Background:

• Invasive aspergillosis is a severe fungal infection, particularly in immunocompromised individuals.
• Pulmonary aspergillosis is common, but urinary tract involvement is infrequent.
• Chronic renal disease increases susceptibility to opportunistic infections.

Observation:

• A 46-year-old male with chronic renal disease presented with intermittent abdominal pain.
• Diagnostic evaluation revealed a fungal ball within the bladder.
• Pathological examination confirmed invasive aspergillosis of the urinary tract.

Findings:

• The patient received multiple antimicrobial and surgical treatments without complete resolution.
• Successful eradication of the fungal infection was achieved with posaconazole therapy.
• This case demonstrates a rare presentation of invasive aspergillosis.

Implications:

• Posaconazole is an effective treatment option for invasive urinary tract aspergillosis.
• Early diagnosis and appropriate antifungal therapy are crucial for managing this rare condition.
• Clinicians should consider fungal infections in immunocompromised patients with renal disease presenting with atypical symptoms.