Related Experiment Video For Barrett dysplasia
Updated: Feb 19, 2026

Diagnosis of Neoplasia in Barrett’s Esophagus using Vital-dye Enhanced Fluorescence Imaging
Published on: May 11, 2014
Diagnosis and Management of Barrett-Related Neoplasia in the Modern Era
Lysandra Voltaggio1, Elizabeth A Montgomery1
1Department of Pathology, Johns Hopkins Medical Institutions, 401 North Broadway, Baltimore, MD 21231, USA.
Abstract:
Whereas in the past, pathologists were hesitant to diagnose high-grade dysplasia in patients with Barrett esophagus, because this diagnosis prompted esophagectomy, current international consensus is that endoscopic treatment is the management for high-grade dysplasia and intramucosal carcinoma. Furthermore, many centers advocate endoscopic ablation for low-grade dysplasia. As such, establishing a diagnosis of dysplasia has become the key step; separation between the grades of dysplasia is less critical. This article offers some criteria for separating dysplasia from reactive changes, discusses pitfalls in interpreting endoscopic mucosal resection specimens, and outlines management strategies.
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