Related Experiment Video
Updated: Feb 19, 2026
10:10
Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
Published on: February 15, 2022
1.9K
Equine Glaucoma.
1BluePearl Veterinary Partners, 3000 Busch Lake Boulevard, Tampa, FL 33614, USA; Brandon Equine Medical Center, 605 E. Bloomingdale Avenue, Brandon, FL 33511, USA.
The Veterinary Clinics of North America. Equine Practice
|November 7, 2017
Summary
Equine glaucoma, a progressive optic nerve disease, is often secondary to uveitis and may be underdiagnosed. Early recognition and treatment are crucial, but the long-term visual prognosis for horses remains poor.
Area of Science:
- Ophthalmology
- Veterinary Medicine
- Neuroscience
Background:
- Glaucoma is a neurodegenerative disease affecting retinal ganglion cells and the optic nerve, potentially causing blindness.
- Equine glaucoma knowledge lags behind human glaucoma, often presenting secondary to uveitis.
- It may be underdiagnosed or misdiagnosed in horses with uveitis.
Purpose of the Study:
- To enhance understanding of equine glaucoma.
- To highlight diagnostic challenges and therapeutic approaches in horses.
- To improve clinician awareness for better recognition and diagnosis.
Main Methods:
- Review of current knowledge on equine glaucoma pathogenesis and clinical presentation.
- Emphasis on diagnostic tools like handheld tonometers.
- Discussion of medical and surgical treatment strategies.
Main Results:
- Equine glaucoma is frequently linked to uveitis.
- Clinician awareness and handheld tonometers improve diagnosis.
- Therapeutic goals include reducing aqueous humor production.
Conclusions:
- Early detection and awareness are vital for managing equine glaucoma.
- Despite treatment, the long-term visual prognosis for affected horses is generally poor.
- Further research into equine glaucoma pathogenesis is warranted.
Related Concept Videos
01:25Glaucoma: Overview
1.5K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.5K
01:28Angle Closure Glaucoma: Treatment
1.4K
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
1.4K
01:27Open Angle Glaucoma: Treatment
1.0K
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
1.0K
01:22Photoreceptors and Visual Pathways
9.5K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
9.5K
01:23Ophthalmic Drug Delivery Systems
54
Ophthalmic drug delivery faces major limitations due to poor absorption across the corneal membrane. This process is primarily driven by diffusion and is influenced by two main factors: the physicochemical properties of the drug and tear drainage. Most ophthalmic drugs, such as pilocarpine, epinephrine, atropine, and local anesthetics, are weak bases. They are typically formulated at an acidic pH to enhance chemical stability. However, this leads to high ionization, reducing their ability to...
54