Related Experiment Video
Updated: Feb 19, 2026

Repressing Gene Transcription by Redirecting Cellular Machinery with Chemical Epigenetic Modifiers
Published on: September 20, 2018
Epigenetic Regulatory Mechanisms Induced by Resveratrol
Guilherme Felipe Santos Fernandes1,2, Gabriel Dalio Bernardes Silva3, Aline Renata Pavan4
1School of Pharmaceutical Sciences, São Paulo State University (UNESP), 14800903 Araraquara, Brazil. guilhermefelipe@outlook.com.
Abstract:
Resveratrol (RVT) is one of the main natural compounds studied worldwide due to its potential therapeutic use in the treatment of many diseases, including cancer, diabetes, cardiovascular diseases, neurodegenerative diseases and metabolic disorders. Nevertheless, the mechanism of action of RVT in all of these conditions is not completely understood, as it can modify not only biochemical pathways but also epigenetic mechanisms. In this paper, we analyze the biological activities exhibited by RVT with a focus on the epigenetic mechanisms, especially those related to DNA methyltransferase (DNMT), histone deacetylase (HDAC) and lysine-specific demethylase-1 (LSD1).
More Related Videos
Related Concept Videos
Epigenetic Regulation
Epigenetic Regulation
X-chromosome...
Constitutive and Regulated Gene Expression
Master Transcription Regulators
Eukaryotic Transcription Inhibitors
Eukaryotic transcription inhibitors usually contain two distinct domains, a...
Co-activators and Co-repressors

