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Related Concept Videos

Skin Cancer01:30

Skin Cancer

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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
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Related Experiment Video

Updated: Feb 19, 2026

Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells
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Multiple Primary Acral Lentiginous Melanomas (MPALM).

Miriam González1, Georgi Tchernev2,3, Anastasiya Atanasova-Chokoeva3

  • 1Department of Internal Medicine, Autonomous University of Honduras (UNAH), Service of Dermatology and Dermatologic Surgery, School University Hospital (HEU), Tegucigalpa 11101, Honduras.

Open Access Macedonian Journal of Medical Sciences
|November 7, 2017
PubMed
Summary

Early detection of acral lentiginous melanoma is crucial. Whole-skin examinations by general practitioners can improve outcomes for this rare foot cancer, which has a poor prognosis.

Keywords:
acral located tumoursamputationsmelanomamultiple primary tumoursstaging

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Area of Science:

  • Dermatology
  • Oncology

Background:

  • Acral lentiginous melanoma (ALM) is a rare subtype of melanoma.
  • ALM commonly occurs on the feet and has a poor prognosis due to late detection.

Purpose of the Study:

  • To highlight a rare case of multiple primary acral lentiginous melanomas of the foot.
  • To emphasize the importance of early detection through whole-skin examinations.

Main Methods:

  • Case report presentation.
  • Review of current literature on ALM management.

Main Results:

  • The case involved a patient with multiple primary ALMs on the foot.
  • Early detection is critical for improving prognosis in ALM.

Conclusions:

  • Whole-skin examinations by general practitioners are vital for early ALM detection.
  • Management should be individualized based on melanoma characteristics and patient risk factors.