Related Experiment Video
Updated: Feb 19, 2026

Development of a Preclinical Inhalation Model to Test Vaporized Cannabis Distillates
Published on: May 30, 2025
Reports of adverse health effects related to synthetic cannabinoid use in New York State
Eleni A Papadopoulos1, Karen R Cummings1, Jeanna M Marraffa2
1New York State Department of Health, Albany, New York.
Background/Objectives:
We assessed synthetic cannabinoid (SC) outbreaks from 2011-2012 and 2015.
Methods:
The National Poison Data System was utilized to collect reports of SC adverse effects in New York State from 2011-2012 and 2015 (N = 713).
Results:
Cases from 2015 were more likely to be admitted to intensive care units and had different symptoms than those in 2011-2012. We identified two new SC structural classes from 2015 samples.
Discussion/Conclusions:
The 2015 outbreak was associated with more severe SC-related illnesses than in 2011-2012.
Scientific Significance:
New SC compounds may pose a different or more severe risk than those previously identified. (Am J Addict 2017;26:772-775).
Related Concept Videos
CNS Stimulants: Cocaine, Amphetamines and Cannabinoids
Stimulants
Cocaine can be administered via snorting, injection, or smoking. It primarily functions by blocking the reuptake of dopamine, resulting in a euphoric high characterized by an intense sensation of happiness and...
Chemotherapy-Induced Nausea and Vomiting: Cannabinoids
Two synthetic agonists of THC,...
Drugs Acting on Autonomic Ganglia: Stimulants
Ganglionic stimulants activate NM nicotinic receptors in autonomic ganglia, falling into two categories: nicotine mimetics [e.g., lobeline, dimethylpiperazine, tetramethylammonium] and muscarinic receptor agonists [e.g., muscarine, methacholine]. The first category's action is rapid and blocked by nicotinic receptor antagonists, while the second category's action is delayed and blocked by atropine-like agents. Nicotine, an alkaloid, affects the heart rate by stimulating...
Effects of Chemicals: Overview
Local Anesthetics: Adverse Effects
Once absorbed into the systemic circulation, local anesthetics can affect the organs that depend on the functioning of sodium...

