Variation in prophylactic antibiotic use for laparoscopic cholecystectomy: need for better stewardship in pediatric

Kibileri Williams1, Lauren Baumann2, Fizan Abdullah2

  • 1Ann & Robert H. Lurie Children's Hospital of Chicago, 225 E. Chicago Ave, Box 63, Chicago, IL, 60611; Northwestern University Feinberg School of Medicine, 420 E. Superior St, Chicago, IL, 60611; Howard University Hospital, 2041 Georgia Avenue NW, Washington, DC, 20060.

Insights

Pediatric surgeons widely use prophylactic antibiotics for laparoscopic cholecystectomy, despite no identified complications in children not receiving them. This highlights variation in antibiotic use and the need for better stewardship.

Area of Science:

  • Pediatric Surgery
  • Surgical Infectious Diseases
  • Antibiotic Stewardship

Background:

  • The use of prophylactic antibiotics for elective laparoscopic cholecystectomy (LC) has been debated.
  • While its use is declining in adults, its application in pediatric surgery is not well-documented.

Purpose of the Study:

  • To investigate the current practices of perioperative antibiotic administration in children undergoing elective LC for symptomatic cholelithiasis or biliary dyskinesia.

Main Methods:

  • A retrospective review of the Pediatric Health Information System (PHIS) database for 2015.
  • Inclusion of patients 18 years or younger who underwent LC for cholelithiasis or biliary dyskinesia.
  • Extraction of demographic, hospital, antibiotic administration, and complication data.

Main Results:

  • 1112 pediatric patients from 44 hospitals were analyzed.
  • Over 80% of hospitals routinely administered prophylactic antibiotics to more than 50% of patients.
  • No surgical complications were observed in patients who did not receive antibiotics.

Conclusions:

  • Significant variation exists in the administration of prophylactic antibiotics for elective pediatric LC across hospitals.
  • Perioperative antibiotic use should be monitored as a quality metric to promote antibiotic stewardship.
Abstract

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