Therapeutic targeting of PP2A

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Assessing Cellular Target Engagement by SHP2 PTPN11 Phosphatase Inhibitors
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Assessing Cellular Target Engagement by SHP2 PTPN11 Phosphatase Inhibitors

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Caitlin M O'Connor1, Abbey Perl1, Daniel Leonard2

  • 1Department of Pharmacology, Case Western Reserve University, Cleveland, OH, 44106, United States.

The International Journal of Biochemistry & Cell Biology
|November 7, 2017
PubMed

Keywords:
ABL-127BortezomibCIP2ACancerCelastrolCell signalingDrug developmentErlotinibFTY720LB-100LCMT-1OP449PME-1PP2APhenothiazinesProtein phosphatase 2AProtein phosphatasesSETSMAPsTumor suppressors

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