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Updated: Feb 19, 2026
Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA
Published on: February 9, 2011
Prevalence of methicillin-resistant Staphylococcus aureus isolated from burn patients in Iran: A systematic review
Mohammad Emaneini1, Reza Beigverdi1, Willem B van Leeuwen2
1Department of Microbiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Objectives:
Methicillin-resistant Staphylococcus aureus (MRSA) is considered a major cause of infection and mortality in burn patients, especially when nosocomially acquired. However, limited information is available on the prevalence of MRSA among burn patients in Iran.
Methods:
A systematic search was performed using different electronic databases including Medline (via PubMed), Embase, Web of Science and Iranian Database. A meta-analysis was performed using Comprehensive Meta-Analysis Software (BioStat v.2.2). Use of a fixed- or random-effects model was used based on a heterogeneity test, and publication bias was assessed using Begg rank correlation and Egger weighted regression methods.
Results:
Of 555 articles published from January 2000 to January 2016, 13 studies were included in this review. The meta-analyses showed that the prevalence of MRSA infection in burn patients was 77.9% (95% confidence interval 70.2-84.0%) among culture-positive cases.
Conclusions:
The results of this study indicate that the prevalence of MRSA among burn patients is very high in Iran. Thus, a comprehensive infection control strategy based on hand hygiene, education and training in antibiotic prescribing, environmental cleaning, contact precautions, good antibiotic stewardship and an active surveillance system on the basis of international criteria is urgently needed.
Insights
Methicillin-resistant Staphylococcus aureus (MRSA) infections are highly prevalent in Iranian burn patients, affecting 77.9% of culture-positive cases. Urgent infection control strategies are needed to combat this significant health threat.
Area of Science:
- Infectious Diseases
- Public Health
- Clinical Microbiology
Background:
- Methicillin-resistant Staphylococcus aureus (MRSA) poses a significant threat to burn patients, leading to increased infection and mortality.
- Limited data exists on the prevalence of MRSA in burn patient populations within Iran.
Purpose of the Study:
- To systematically review and meta-analyze the prevalence of MRSA infections among burn patients in Iran.
- To inform the development of targeted infection control strategies.
Main Methods:
- A systematic literature search was conducted across major electronic databases (Medline, Embase, Web of Science, Iranian Database).
- A meta-analysis was performed on 13 selected studies published between January 2000 and January 2016.
- Heterogeneity and publication bias were assessed using established statistical methods.
Main Results:
- The meta-analysis included 13 studies encompassing data from January 2000 to January 2016.
- The overall prevalence of MRSA infection in culture-positive burn patients in Iran was found to be 77.9% (95% CI: 70.2-84.0%).
Conclusions:
- The prevalence of MRSA among burn patients in Iran is notably high.
- Comprehensive infection control measures, including hand hygiene, antibiotic stewardship, environmental cleaning, and surveillance, are urgently required.
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